RBL2

Summary:

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Name
OMIM ID
Ensembl ID
HGNC ID
PHARMGKB ID
Map Location
NameRB transcriptional corepressor like 2
OMIM IDMIM:180203
Ensembl IDEnsembl:ENSG00000103479
HGNC IDHGNC:HGNC:9894
PHARMGKB IDPA34258
Map Location16q12.2

GO terms in RBL2


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Term Type
Evidence Type
GO Term ID
GO Des.
BP IEA GO:0006325 chromatin organization
BP IEA GO:0006351 transcription, DNA-templated
BP IEA GO:0006357 regulation of transcription by RNA polymerase II
BP TAS GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
BP IBA GO:0007346 regulation of mitotic cell cycle
BP IMP GO:0010629 negative regulation of gene expression
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Gene expression in normal tissue: RBL2

16 tissues mixtureadiposeadrenalbrainbreastcolonheartkidneyliverlunglymph nodeovaryprostateskeletal muscletestesthyroidwhite blood cells

Gene-model tissue-cancer distribution: Bubble Plot

LUNtissue: LUN cancer: LUNG model num: 0LUNGtissue: LUNG cancer: undefined model num: 3undefinetissue: undefine cancer: undefined model num: 0undefinedtissue: undefined cancer: PANCAN model num: 59BOWEtissue: BOWE cancer: BOWEL model num: 0BOWELtissue: BOWEL cancer: undefined model num: 3

Gene-drug pathway distribution

undefined21PI3K/MTOR signaling1Metabolism1Apoptosis regulation1Biosynthesis of secondary metabolites1Cell cycle1Chromatin histone acetylation1

Pathways in RBL2


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Database
Pathway ID
Pathway Des.
pid e2f_pathway E2F transcription factor network
pid foxopathway FoxO family signaling
kegg hsa04068 FoxO signaling pathway - Homo sapiens (human)
kegg hsa04110 Cell cycle - Homo sapiens (human)
kegg hsa04151 PI3K-Akt signaling pathway - Homo sapiens (human)
kegg hsa04218 Cellular senescence - Homo sapiens (human)
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Gene-Drug: Aster Plot


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Drug ID
Drug Name
Model Num.
iGMDRD579 PF750 2
iGMDRD772 BRD4770 2
iGMDRD494 Neopeltolide 2
iGMDRD446 LY 2183240 2
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Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in RBL2

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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