SEARCH

HOME / SEARCH / LIN9

LIN9

Summary: This gene encodes a tumor suppressor protein that inhibits DNA synthesis and oncogenic transformation through association with the retinoblastoma 1 protein. The encoded protein also interacts with a complex of other cell cycle regulators to repress cell cycle-dependent gene expression in non-dividing cells. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jul 2012].

Loading, please wait...

Name	OMIM ID	Ensembl ID	HGNC ID	PHARMGKB ID	Map Location
Namelin-9 DREAM MuvB core complex component OMIM IDMIM:609375 Ensembl IDEnsembl:ENSG00000183814 HGNC IDHGNC:HGNC:30830 PHARMGKB IDPA134970771 Map Location1q42.12

Gene Categories:

TUMOR SUPPRESSOR

GO terms in LIN9

Loading, please wait...

Term Type	Evidence Type	GO Term ID	GO Des.
CC	IBA	GO:0005654	nucleoplasm
CC	IDA	GO:0005654	nucleoplasm
CC	TAS	GO:0005654	nucleoplasm
CC	IEA	GO:0017053	transcriptional repressor complex
BP	IBA	GO:0000003	reproduction
BP	IEA	GO:0006351	transcription, DNA-templated

Showing 1 to 6 of 13 rows rows per page

Gene expression in normal tissue: LIN9

Select Project:

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in LIN9

Loading, please wait...

Database	Pathway ID	Pathway Des.
reactome	R-HSA-1362277	Transcription of E2F targets under negative control by DREAM complex
reactome	R-HSA-1362277	Transcription of E2F targets under negative control by DREAM complex
reactome	R-HSA-1362300	Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1
reactome	R-HSA-1538133	G0 and Early G1
reactome	R-HSA-1538133	G0 and Early G1
reactome	R-HSA-156711	Polo-like kinase mediated events

Showing 1 to 6 of 22 rows rows per page

Gene-Drug: Aster Plot

Loading, please wait...

Drug ID	Drug Name	Model Num.
iGMDRD289	Parthenolide	3
iGMDRD705	Nakiterpiosin	6
iGMDRD255	SB225002	3
iGMDRD260	FQI-2	3

Showing 1 to 4 of 21 rows rows per page

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in LIN9

Loading, please wait...

	Model	Level	Reference ID	Tissue	Cancer	Drug	Clinical Response	Source
No matching records found

SITE

DATATYPES

CLASSFICATION

Disclaimer: iGMDR is intended for research purposes only. Its information cannot be used for emergencies or medical or professional advice.