AMZ2
Summary: The protein encoded by this gene is a zinc metalloprotease that displays some activity against angiotensin-3. The encoded protein is inhibited by the aminopeptidase inhibitor amastatin, as well as by the general inhibitors o-phenanthroline and batimastat. Defects in this gene may be associated with lung tumorigenesis. [provided by RefSeq, Oct 2016].
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Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
OMIM IDMIM:615169 Ensembl IDEnsembl:ENSG00000196704 HGNC IDHGNC:HGNC:28041 PHARMGKB IDPA162376414 Map Location17q24.2 | |||||
GO terms in AMZ2
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Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| MF | IMP | GO:0008233 | peptidase activity |
| MF | IEA | GO:0008237 | metallopeptidase activity |
| MF | IEA | GO:0008270 | zinc ion binding |
| BP | IMP | GO:0006508 | proteolysis |
| CC | ND | GO:0005575 | cellular_component |
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Gene expression in normal tissue: AMZ2
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in AMZ2
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Database | Pathway ID | Pathway Des. |
|---|---|---|
| No matching records found | ||
Gene-Drug: Aster Plot
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in AMZ2
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Model | Level | Reference ID | Tissue | Cancer | Drug | Clinical Response | Source | |
|---|---|---|---|---|---|---|---|---|
| No matching records found | ||||||||
CLASSFICATION
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