DYRK1B
Summary: This gene encodes a member of a family of nuclear-localized protein kinases. The encoded protein participates in the regulation of the cell cycle. Expression of this gene may be altered in tumor cells, and mutations in this gene were found to cause abdominal obesity-metabolic syndrome 3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014].
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Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
---|---|---|---|---|---|
OMIM IDMIM:604556 Ensembl IDEnsembl:ENSG00000105204 HGNC IDHGNC:HGNC:3092 PHARMGKB IDPA27549 Map Location19q13.2 |
GO terms in DYRK1B
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Term Type | Evidence Type | GO Term ID | GO Des. |
---|---|---|---|
CC | IDA | GO:0005634 | nucleus |
BP | IDA | GO:0006468 | protein phosphorylation |
BP | IEA | GO:0007520 | myoblast fusion |
BP | IEA | GO:0018108 | peptidyl-tyrosine phosphorylation |
BP | IDA | GO:0045893 | positive regulation of transcription, DNA-templated |
BP | IMP | GO:0060612 | adipose tissue development |
Gene expression in normal tissue: DYRK1B
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in DYRK1B
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Database | Pathway ID | Pathway Des. |
---|---|---|
netpath | Pathway_EGFR1 | EGFR1 |
netpath | Pathway_TCR | TCR |
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Gene-Drug: Aster Plot
Gene in drug-gene network: Network Plot

Gene-drug targets distribution
Gene Structure: PDB
Models in DYRK1B
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Model | Level | Reference ID | Tissue | Cancer | Drug | Clinical Response | Source | |
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No matching records found |