TFPT


Summary:

NameOMIM IDEnsembl IDHGNC IDPHARMGKB IDMap Location
TCF3 fusion partnerMIM:609519Ensembl:ENSG00000105619HGNC:HGNC:13630PA3780219q13.42

Gene Categories:

DNA REPAIR

GO terms in TFPT


Term TypeEvidence TypeGO Term IDGO Des.
CCISSGO:0005634nucleus
CCIDAGO:0005654nucleoplasm
CCTASGO:0005654nucleoplasm
CCISSGO:0005737cytoplasm
CCIBAGO:0031011Ino80 complex
CCIDAGO:0031011Ino80 complex
CCIDAGO:0031965nuclear membrane
BPIEAGO:0006281DNA repair
BPIEAGO:0006310DNA recombination
BPIEAGO:0006351transcription, DNA-templated
BPIEAGO:0006355regulation of transcription, DNA-templated
BPIBAGO:0006915apoptotic process
BPTASGO:0016579protein deubiquitination
BPIDAGO:0097190apoptotic signaling pathway
MFIBAGO:0003677DNA binding
MFISSGO:0003677DNA binding
MFIPIGO:0005515protein binding

Gene expression in normal tissue: TFPT

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in TFPT


DatabasePathway IDPathway Des.
reactomeR-HSA-392499Metabolism of proteins
reactomeR-HSA-5688426Deubiquitination
reactomeR-HSA-5689603UCH proteinases
reactomeR-HSA-5696394DNA Damage Recognition in GG-NER
reactomeR-HSA-5696398Nucleotide Excision Repair
reactomeR-HSA-5696399Global Genome Nucleotide Excision Repair (GG-NER)
reactomeR-HSA-597592Post-translational protein modification
reactomeR-HSA-73894DNA Repair

Gene-Drug: Aster Plot


Drug IDDrug NameModel Num.
iGMDRD872BRD71373
iGMDRD399Selumetinib2
iGMDRD414MST-3123
iGMDRD871BRD63686
iGMDRD506Fedratinib6
iGMDRD329Merck603
iGMDRD369TGX-1152
iGMDRD300Tozasertib3
iGMDRD505Pevonedistat2
iGMDRD23Gossypol4
iGMDRD137Indisulam3
iGMDRD121GMX17783
iGMDRD474Avrainvillamide6
iGMDRD103SN-382
iGMDRD255SB2250022
iGMDRD782DC-45-A22
iGMDRD267Oligomycin A3
iGMDRD85Ursolic acid2
iGMDRD61Kinetin riboside4
iGMDRD351GW843682X2
iGMDRD945ML2143
iGMDRD307Manumycin A1
iGMDRD126Tipifarnib3
iGMDRD1008SR-II-138A1
iGMDRD512nutlin 35
iGMDRD546BMS-7548072
iGMDRD560MK-22062
iGMDRD405PIK-755

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in TFPT

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