TFPT
Summary:
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| TCF3 fusion partner | MIM:609519 | Ensembl:ENSG00000105619 | HGNC:HGNC:13630 | PA37802 | 19q13.42 |
Gene Categories:
DNA REPAIRGO terms in TFPT
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| CC | ISS | GO:0005634 | nucleus |
| CC | IDA | GO:0005654 | nucleoplasm |
| CC | TAS | GO:0005654 | nucleoplasm |
| CC | ISS | GO:0005737 | cytoplasm |
| CC | IBA | GO:0031011 | Ino80 complex |
| CC | IDA | GO:0031011 | Ino80 complex |
| CC | IDA | GO:0031965 | nuclear membrane |
| BP | IEA | GO:0006281 | DNA repair |
| BP | IEA | GO:0006310 | DNA recombination |
| BP | IEA | GO:0006351 | transcription, DNA-templated |
| BP | IEA | GO:0006355 | regulation of transcription, DNA-templated |
| BP | IBA | GO:0006915 | apoptotic process |
| BP | TAS | GO:0016579 | protein deubiquitination |
| BP | IDA | GO:0097190 | apoptotic signaling pathway |
| MF | IBA | GO:0003677 | DNA binding |
| MF | ISS | GO:0003677 | DNA binding |
| MF | IPI | GO:0005515 | protein binding |
Gene expression in normal tissue: TFPT
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in TFPT
| Database | Pathway ID | Pathway Des. |
|---|---|---|
| reactome | R-HSA-392499 | Metabolism of proteins |
| reactome | R-HSA-5688426 | Deubiquitination |
| reactome | R-HSA-5689603 | UCH proteinases |
| reactome | R-HSA-5696394 | DNA Damage Recognition in GG-NER |
| reactome | R-HSA-5696398 | Nucleotide Excision Repair |
| reactome | R-HSA-5696399 | Global Genome Nucleotide Excision Repair (GG-NER) |
| reactome | R-HSA-597592 | Post-translational protein modification |
| reactome | R-HSA-73894 | DNA Repair |
Gene-Drug: Aster Plot
| Drug ID | Drug Name | Model Num. |
|---|---|---|
| iGMDRD872 | BRD7137 | 3 |
| iGMDRD399 | Selumetinib | 2 |
| iGMDRD414 | MST-312 | 3 |
| iGMDRD871 | BRD6368 | 6 |
| iGMDRD506 | Fedratinib | 6 |
| iGMDRD329 | Merck60 | 3 |
| iGMDRD369 | TGX-115 | 2 |
| iGMDRD300 | Tozasertib | 3 |
| iGMDRD505 | Pevonedistat | 2 |
| iGMDRD23 | Gossypol | 4 |
| iGMDRD137 | Indisulam | 3 |
| iGMDRD121 | GMX1778 | 3 |
| iGMDRD474 | Avrainvillamide | 6 |
| iGMDRD103 | SN-38 | 2 |
| iGMDRD255 | SB225002 | 2 |
| iGMDRD782 | DC-45-A2 | 2 |
| iGMDRD267 | Oligomycin A | 3 |
| iGMDRD85 | Ursolic acid | 2 |
| iGMDRD61 | Kinetin riboside | 4 |
| iGMDRD351 | GW843682X | 2 |
| iGMDRD945 | ML214 | 3 |
| iGMDRD307 | Manumycin A | 1 |
| iGMDRD126 | Tipifarnib | 3 |
| iGMDRD1008 | SR-II-138A | 1 |
| iGMDRD512 | nutlin 3 | 5 |
| iGMDRD546 | BMS-754807 | 2 |
| iGMDRD560 | MK-2206 | 2 |
| iGMDRD405 | PIK-75 | 5 |
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in TFPT
CLASSFICATION
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Disclaimer: iGMDR is intended for research purposes only. Its information cannot be used for emergencies or medical or professional advice.