CSNK1G2
Summary:
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| casein kinase 1 gamma 2 | MIM:602214 | Ensembl:ENSG00000133275 | HGNC:HGNC:2455 | PA26955 | 19p13.3 |
GO terms in CSNK1G2
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| CC | IBA | GO:0005634 | nucleus |
| CC | IBA | GO:0005737 | cytoplasm |
| CC | TAS | GO:0005829 | cytosol |
| CC | HDA | GO:0016020 | membrane |
| BP | TAS | GO:0006468 | protein phosphorylation |
| BP | IBA | GO:0006897 | endocytosis |
| BP | TAS | GO:0007165 | signal transduction |
| BP | IBA | GO:0018105 | peptidyl-serine phosphorylation |
| BP | IDA | GO:0018105 | peptidyl-serine phosphorylation |
| BP | TAS | GO:0030148 | sphingolipid biosynthetic process |
| BP | IEA | GO:0046777 | protein autophosphorylation |
| MF | IEA | GO:0000287 | magnesium ion binding |
| MF | IBA | GO:0004674 | protein serine/threonine kinase activity |
| MF | IDA | GO:0004674 | protein serine/threonine kinase activity |
| MF | TAS | GO:0004674 | protein serine/threonine kinase activity |
| MF | IPI | GO:0005515 | protein binding |
| MF | IEA | GO:0005524 | ATP binding |
| MF | IEA | GO:0042277 | peptide binding |
| MF | IEA | GO:0051219 | phosphoprotein binding |
Gene expression in normal tissue: CSNK1G2
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in CSNK1G2
| Database | Pathway ID | Pathway Des. |
|---|---|---|
| reactome | R-HSA-1430728 | Metabolism |
| reactome | R-HSA-162582 | Signal Transduction |
| reactome | R-HSA-1660661 | Sphingolipid de novo biosynthesis |
| reactome | R-HSA-195721 | Signaling by WNT |
| reactome | R-HSA-201681 | TCF dependent signaling in response to WNT |
| reactome | R-HSA-428157 | Sphingolipid metabolism |
| reactome | R-HSA-4641262 | Disassembly of the destruction complex and recruitment of AXIN to the membrane |
| reactome | R-HSA-556833 | Metabolism of lipids |
| pid | foxopathway | FoxO family signaling |
| pid | hedgehog_glipathway | Hedgehog signaling events mediated by Gli proteins |
| pid | p53regulationpathway | p53 pathway |
| kegg | hsa04340 | Hedgehog signaling pathway - Homo sapiens (human) |
| wikipathways | WP4249 | Hedgehog Signaling Pathway |
Gene-Drug: Aster Plot
| Drug ID | Drug Name | Model Num. |
|---|---|---|
| iGMDRD210 | AC55649 | 1 |
| iGMDRD577 | BIX01294 | 3 |
| iGMDRD105 | Triptolide | 2 |
| iGMDRD289 | Parthenolide | 1 |
| iGMDRD945 | ML214 | 8 |
| iGMDRD318 | PAC-1 | 1 |
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in CSNK1G2
CLASSFICATION
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