FSTL3
Summary: Follistatin-like 3 is a secreted glycoprotein of the follistatin-module-protein family. It may have a role in leukemogenesis. [provided by RefSeq, Jul 2008].
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Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
OMIM IDMIM:605343 Ensembl IDEnsembl:ENSG00000070404 HGNC IDHGNC:HGNC:3973 PHARMGKB IDPA28390 Map Location19p13.3 | |||||
Gene Categories:
DRUGGABLE GENOMEGO terms in FSTL3
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Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| MF | IPI | GO:0001968 | fibronectin binding |
| MF | IPI | GO:0005515 | protein binding |
| MF | IPI | GO:0048185 | activin binding |
| CC | TAS | GO:0005576 | extracellular region |
| CC | IDA | GO:0005615 | extracellular space |
| CC | IDA | GO:0005634 | nucleus |
Gene expression in normal tissue: FSTL3
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in FSTL3
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Database | Pathway ID | Pathway Des. |
|---|---|---|
| reactome | R-HSA-1502540 | Signaling by Activin |
| reactome | R-HSA-162582 | Signal Transduction |
| reactome | R-HSA-2473224 | Antagonism of Activin by Follistatin |
| reactome | R-HSA-381426 | Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) |
| reactome | R-HSA-392499 | Metabolism of proteins |
| reactome | R-HSA-597592 | Post-translational protein modification |
Gene-Drug: Aster Plot
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in FSTL3
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Model | Level | Reference ID | Tissue | Cancer | Drug | Clinical Response | Source | |
|---|---|---|---|---|---|---|---|---|
| No matching records found | ||||||||
CLASSFICATION
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