CDK18
Summary:
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| cyclin dependent kinase 18 | MIM:169190 | Ensembl:ENSG00000117266 | HGNC:HGNC:8751 | PA33097 | 1q32.1 |
GO terms in CDK18
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| CC | ND | GO:0005575 | cellular_component |
| CC | IBA | GO:0005634 | nucleus |
| CC | IBA | GO:0005737 | cytoplasm |
| BP | IBA | GO:0006468 | protein phosphorylation |
| MF | IBA | GO:0004674 | protein serine/threonine kinase activity |
| MF | IBA | GO:0004693 | cyclin-dependent protein serine/threonine kinase activity |
| MF | IPI | GO:0005515 | protein binding |
| MF | IEA | GO:0005524 | ATP binding |
Gene expression in normal tissue: CDK18
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in CDK18
| Database | Pathway ID | Pathway Des. |
|---|
Gene-Drug: Aster Plot
| Drug ID | Drug Name | Model Num. |
|---|---|---|
| iGMDRD147 | Prima-1 | 3 |
| iGMDRD524 | ISX-9 | 3 |
| iGMDRD188 | Piperlongumine | 2 |
| iGMDRD887 | Compound 23 citrate | 2 |
| iGMDRD872 | BRD7137 | 2 |
| iGMDRD577 | BIX01294 | 3 |
| iGMDRD562 | Navitoclax | 3 |
| iGMDRD780 | PP-30 | 2 |
| iGMDRD289 | Parthenolide | 5 |
| iGMDRD481 | Dactolisib | 3 |
| iGMDRD474 | Avrainvillamide | 2 |
| iGMDRD137 | Indisulam | 2 |
| iGMDRD255 | SB225002 | 3 |
| iGMDRD211 | (1S,3R)-RSL3 | 1 |
| iGMDRD466 | Chaetocin | 3 |
| iGMDRD634 | SCHEMBL2608041 | 2 |
| iGMDRD511 | CHEMBL399379 | 3 |
| iGMDRD154 | NSC23766 | 3 |
| iGMDRD945 | ML214 | 3 |
| iGMDRD446 | LY 2183240 | 2 |
| iGMDRD85 | Ursolic acid | 3 |
| iGMDRD163 | all trans Retinoic Acid | 3 |
| iGMDRD150 | RITA | 1 |
| iGMDRD427 | ABT737 | 3 |
| iGMDRD483 | SCH-529074 | 6 |
| iGMDRD523 | Cyanoquinoline, 11 | 3 |
| iGMDRD781 | Sirolimus | 2 |
| iGMDRD126 | Tipifarnib | 5 |
| iGMDRD307 | Manumycin A | 3 |
| iGMDRD210 | AC55649 | 1 |
| iGMDRD889 | Compound 7d-cis | 2 |
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in CDK18
CLASSFICATION
Copyright © 2018 Modellab | All Rights Reserved
Disclaimer: iGMDR is intended for research purposes only. Its information cannot be used for emergencies or medical or professional advice.