GPR87
Summary: This gene encodes a G protein-coupled receptor and is located in a cluster of G protein-couple receptor genes on chromosome 3. The encoded protein has been shown to be overexpressed in lung squamous cell carcinoma (PMID:18057535) and regulated by p53 (PMID:19602589). [provided by RefSeq, Nov 2011].
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| G protein-coupled receptor 87 | MIM:606379 | Ensembl:ENSG00000138271 | HGNC:HGNC:4538 | PA28931 | 3q25.1 |
GO terms in GPR87
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| MF | IBA | GO:0045028 | G-protein coupled purinergic nucleotide receptor activity |
| BP | IBA | GO:0007186 | G-protein coupled receptor signaling pathway |
| BP | IEA | GO:0007194 | negative regulation of adenylate cyclase activity |
| BP | ND | GO:0008150 | biological_process |
| BP | IEA | GO:0035589 | G-protein coupled purinergic nucleotide receptor signaling pathway |
Gene expression in normal tissue: GPR87
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Gene-Drug: Aster Plot
| Drug ID | Drug Name | Model Num. |
|---|---|---|
| iGMDRD424 | Tamatinib | 1 |
| iGMDRD546 | BMS-754807 | 2 |
| iGMDRD427 | ABT737 | 3 |
| iGMDRD84 | Lovastatin acid | 1 |
| iGMDRD451 | Serdemetan | 2 |
| iGMDRD945 | ML214 | 3 |
| iGMDRD901 | ELCPK | 3 |
| iGMDRD64 | Parbendazole | 3 |
| iGMDRD577 | BIX01294 | 5 |
| iGMDRD61 | Kinetin riboside | 2 |
| iGMDRD193 | Fqi1 | 3 |
| iGMDRD133 | Lapatinib | 1 |
| iGMDRD446 | LY 2183240 | 4 |
| iGMDRD871 | BRD6368 | 2 |
| iGMDRD399 | Selumetinib | 3 |
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in GPR87
CLASSFICATION
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