GPR87


Summary: This gene encodes a G protein-coupled receptor and is located in a cluster of G protein-couple receptor genes on chromosome 3. The encoded protein has been shown to be overexpressed in lung squamous cell carcinoma (PMID:18057535) and regulated by p53 (PMID:19602589). [provided by RefSeq, Nov 2011].

NameOMIM IDEnsembl IDHGNC IDPHARMGKB IDMap Location
G protein-coupled receptor 87MIM:606379Ensembl:ENSG00000138271HGNC:HGNC:4538PA289313q25.1

GO terms in GPR87


Term TypeEvidence TypeGO Term IDGO Des.
MFIBAGO:0045028G-protein coupled purinergic nucleotide receptor activity
BPIBAGO:0007186G-protein coupled receptor signaling pathway
BPIEAGO:0007194negative regulation of adenylate cyclase activity
BPNDGO:0008150biological_process
BPIEAGO:0035589G-protein coupled purinergic nucleotide receptor signaling pathway

Gene expression in normal tissue: GPR87

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in GPR87


DatabasePathway IDPathway Des.
wikipathwaysWP455GPCRs, Class A Rhodopsin-like

Gene-Drug: Aster Plot


Drug IDDrug NameModel Num.
iGMDRD424Tamatinib1
iGMDRD546BMS-7548072
iGMDRD427ABT7373
iGMDRD84Lovastatin acid1
iGMDRD451Serdemetan2
iGMDRD945ML2143
iGMDRD901ELCPK3
iGMDRD64Parbendazole3
iGMDRD577BIX012945
iGMDRD61Kinetin riboside2
iGMDRD193Fqi13
iGMDRD133Lapatinib1
iGMDRD446LY 21832404
iGMDRD871BRD63682
iGMDRD399Selumetinib3

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in GPR87

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