GPR87
Summary: This gene encodes a G protein-coupled receptor and is located in a cluster of G protein-couple receptor genes on chromosome 3. The encoded protein has been shown to be overexpressed in lung squamous cell carcinoma (PMID:18057535) and regulated by p53 (PMID:19602589). [provided by RefSeq, Nov 2011].
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Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
OMIM IDMIM:606379 Ensembl IDEnsembl:ENSG00000138271 HGNC IDHGNC:HGNC:4538 PHARMGKB IDPA28931 Map Location3q25.1 | |||||
GO terms in GPR87
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Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| MF | IBA | GO:0045028 | G-protein coupled purinergic nucleotide receptor activity |
| BP | IBA | GO:0007186 | G-protein coupled receptor signaling pathway |
| BP | IEA | GO:0007194 | negative regulation of adenylate cyclase activity |
| BP | ND | GO:0008150 | biological_process |
| BP | IEA | GO:0035589 | G-protein coupled purinergic nucleotide receptor signaling pathway |
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Gene expression in normal tissue: GPR87
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in GPR87
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Database | Pathway ID | Pathway Des. |
|---|---|---|
| wikipathways | WP455 | GPCRs, Class A Rhodopsin-like |
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Gene-Drug: Aster Plot
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in GPR87
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Model | Level | Reference ID | Tissue | Cancer | Drug | Clinical Response | Source | |
|---|---|---|---|---|---|---|---|---|
| No matching records found | ||||||||
CLASSFICATION
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