TAOK2

Summary: This gene encodes a serine/threonine protein kinase that is involved in many different processes, including, cell signaling, microtubule organization and stability, and apoptosis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Oct 2011].

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Name
OMIM ID
Ensembl ID
HGNC ID
PHARMGKB ID
Map Location
NameTAO kinase 2
OMIM IDMIM:613199
Ensembl IDEnsembl:ENSG00000149930
HGNC IDHGNC:HGNC:16835
PHARMGKB IDPA134907964
Map Location16p11.2

GO terms in TAOK2


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Term Type
Evidence Type
GO Term ID
GO Des.
MF IBA GO:0004674 protein serine/threonine kinase activity
MF IDA GO:0004674 protein serine/threonine kinase activity
MF NAS GO:0004674 protein serine/threonine kinase activity
MF IBA GO:0004709 MAP kinase kinase kinase activity
MF NAS GO:0004709 MAP kinase kinase kinase activity
MF IEA GO:0005524 ATP binding
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Gene expression in normal tissue: TAOK2

Gene-model tissue-cancer distribution: Bubble Plot

undefinetissue: undefine cancer: undefined model num: 0undefinedtissue: undefined cancer: PANCAN model num: 24BOWEtissue: BOWE cancer: BOWEL model num: 0BOWELtissue: BOWEL cancer: undefined model num: 17LUNtissue: LUN cancer: LUNG model num: 0LUNGtissue: LUNG cancer: undefined model num: 5OVARtissue: OVAR cancer: OVARY model num: 0OVARYtissue: OVARY cancer: undefined model num: 1

Gene-drug pathway distribution

undefined16PI3K/MTOR signaling1Apoptosis regulation1Leukocyte transendothelial migration1Chromatin histone acetylation1ERK MAPK signaling1

Pathways in TAOK2


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Database
Pathway ID
Pathway Des.
pid p38_mkk3_6pathway p38 MAPK signaling pathway
kegg hsa04010 MAPK signaling pathway - Homo sapiens (human)
wikipathways WP382 MAPK Signaling Pathway
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Gene-Drug: Aster Plot


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Drug ID
Drug Name
Model Num.
iGMDRD289 Parthenolide 1
iGMDRD782 DC-45-A2 5
iGMDRD294 Batimastat 1
iGMDRD870 BRD63610 2
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Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in TAOK2

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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