CPNE5
Summary: Calcium-dependent membrane-binding proteins may regulate molecular events at the interface of the cell membrane and cytoplasm. This gene is one of several genes that encode a calcium-dependent protein containing two N-terminal type II C2 domains and an integrin A domain-like sequence in the C-terminus. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. More variants may exist, but their full-length natures could not be determined. [provided by RefSeq, Sep 2015].
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| copine 5 | MIM:604209 | Ensembl:ENSG00000124772 | HGNC:HGNC:2318 | PA26835 | 6p21.2 |
GO terms in CPNE5
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| BP | IBA | GO:0071277 | cellular response to calcium ion |
| BP | IDA | GO:1903861 | positive regulation of dendrite extension |
| CC | IBA | GO:0005886 | plasma membrane |
| CC | IEA | GO:0043005 | neuron projection |
| CC | IEA | GO:0043204 | perikaryon |
| CC | HDA | GO:0070062 | extracellular exosome |
| MF | ND | GO:0003674 | molecular_function |
| MF | IBA | GO:0005544 | calcium-dependent phospholipid binding |
Gene expression in normal tissue: CPNE5
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in CPNE5
| Database | Pathway ID | Pathway Des. |
|---|
Gene-Drug: Aster Plot
| Drug ID | Drug Name | Model Num. |
|---|---|---|
| iGMDRD456 | Crizotinib | 1 |
| iGMDRD289 | Parthenolide | 1 |
| iGMDRD121 | GMX1778 | 1 |
| iGMDRD84 | Lovastatin acid | 3 |
| iGMDRD126 | Tipifarnib | 3 |
| iGMDRD322 | FK 866 | 1 |
| iGMDRD945 | ML214 | 3 |
| iGMDRD353 | PD0325901 | 1 |
| iGMDRD871 | BRD6368 | 3 |
| iGMDRD366 | PI-103 | 3 |
| iGMDRD351 | GW843682X | 3 |
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in CPNE5
CLASSFICATION
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