CPNE5


Summary: Calcium-dependent membrane-binding proteins may regulate molecular events at the interface of the cell membrane and cytoplasm. This gene is one of several genes that encode a calcium-dependent protein containing two N-terminal type II C2 domains and an integrin A domain-like sequence in the C-terminus. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. More variants may exist, but their full-length natures could not be determined. [provided by RefSeq, Sep 2015].

NameOMIM IDEnsembl IDHGNC IDPHARMGKB IDMap Location
copine 5MIM:604209Ensembl:ENSG00000124772HGNC:HGNC:2318PA268356p21.2

GO terms in CPNE5


Term TypeEvidence TypeGO Term IDGO Des.
BPIBAGO:0071277cellular response to calcium ion
BPIDAGO:1903861positive regulation of dendrite extension
CCIBAGO:0005886plasma membrane
CCIEAGO:0043005neuron projection
CCIEAGO:0043204perikaryon
CCHDAGO:0070062extracellular exosome
MFNDGO:0003674molecular_function
MFIBAGO:0005544calcium-dependent phospholipid binding

Gene expression in normal tissue: CPNE5

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in CPNE5


DatabasePathway IDPathway Des.

Gene-Drug: Aster Plot


Drug IDDrug NameModel Num.
iGMDRD456Crizotinib1
iGMDRD289Parthenolide1
iGMDRD121GMX17781
iGMDRD84Lovastatin acid3
iGMDRD126Tipifarnib3
iGMDRD322FK 8661
iGMDRD945ML2143
iGMDRD353PD03259011
iGMDRD871BRD63683
iGMDRD366PI-1033
iGMDRD351GW843682X3

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in CPNE5

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