NUAK2
Summary:
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| NUAK family kinase 2 | MIM:608131 | Ensembl:ENSG00000163545 | HGNC:HGNC:29558 | PA142671243 | 1q32.1 |
GO terms in NUAK2
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| CC | IBA | GO:0005634 | nucleus |
| CC | IBA | GO:0005737 | cytoplasm |
| BP | IBA | GO:0006468 | protein phosphorylation |
| BP | IDA | GO:0006468 | protein phosphorylation |
| BP | IEA | GO:0006915 | apoptotic process |
| BP | IDA | GO:0030036 | actin cytoskeleton organization |
| BP | IBA | GO:0035556 | intracellular signal transduction |
| BP | IDA | GO:0042149 | cellular response to glucose starvation |
| BP | IDA | GO:0043066 | negative regulation of apoptotic process |
| MF | IDA | GO:0000287 | magnesium ion binding |
| MF | IBA | GO:0004674 | protein serine/threonine kinase activity |
| MF | IDA | GO:0004674 | protein serine/threonine kinase activity |
| MF | IBA | GO:0004679 | AMP-activated protein kinase activity |
| MF | IPI | GO:0005515 | protein binding |
| MF | IDA | GO:0005524 | ATP binding |
| MF | IBA | GO:0035174 | histone serine kinase activity |
Gene expression in normal tissue: NUAK2
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in NUAK2
| Database | Pathway ID | Pathway Des. |
|---|
Gene-Drug: Aster Plot
| Drug ID | Drug Name | Model Num. |
|---|---|---|
| iGMDRD446 | LY 2183240 | 3 |
| iGMDRD237 | ABT-751 | 3 |
| iGMDRD280 | CYTOCHALASIN B | 5 |
| iGMDRD394 | BX-795 | 3 |
| iGMDRD945 | ML214 | 3 |
| iGMDRD433 | Lexibulin | 1 |
| iGMDRD584 | VER 155008 | 3 |
| iGMDRD424 | Tamatinib | 3 |
| iGMDRD523 | Cyanoquinoline, 11 | 3 |
| iGMDRD662 | JQ-1 | 3 |
| iGMDRD562 | Navitoclax | 6 |
| iGMDRD505 | Pevonedistat | 4 |
| iGMDRD552 | AZD-1775 | 1 |
| iGMDRD64 | Parbendazole | 3 |
| iGMDRD60 | Quinoclamine | 3 |
| iGMDRD158 | NSC141540 | 3 |
| iGMDRD5 | Tyrphostin AG 1478 | 6 |
| iGMDRD105 | Triptolide | 5 |
| iGMDRD782 | DC-45-A2 | 3 |
| iGMDRD870 | BRD63610 | 3 |
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in NUAK2
CLASSFICATION
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