XPO5
Summary: This gene encodes a member of the karyopherin family that is required for the transport of small RNAs and double-stranded RNA-binding proteins from the nucleus to the cytoplasm. The encoded protein translocates cargo through the nuclear pore complex in a RanGTP-dependent process. [provided by RefSeq, Aug 2011].
Loading, please wait...
Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
Nameexportin 5 OMIM IDMIM:607845 Ensembl IDEnsembl:ENSG00000124571 HGNC IDHGNC:HGNC:17675 PHARMGKB IDPA134979214 Map Location6p21.1 | |||||
Gene Categories:
TRANSPORTERGO terms in XPO5
Loading, please wait...
Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| MF | IEA | GO:0000049 | tRNA binding |
| MF | HDA | GO:0003723 | RNA binding |
| MF | IBA | GO:0003723 | RNA binding |
| MF | TAS | GO:0003723 | RNA binding |
| MF | IDA | GO:0003729 | mRNA binding |
| MF | IBA | GO:0005049 | nuclear export signal receptor activity |
Gene expression in normal tissue: XPO5
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in XPO5
Loading, please wait...
Database | Pathway ID | Pathway Des. |
|---|---|---|
| reactome | R-HSA-203927 | MicroRNA (miRNA) biogenesis |
| reactome | R-HSA-211000 | Gene Silencing by RNA |
| reactome | R-HSA-74160 | Gene expression (Transcription) |
| kegg | hsa03013 | RNA transport - Homo sapiens (human) |
| wikipathways | WP2338 | miRNA Biogenesis |
| wikipathways | WP2805 | RNA interference |
Showing 1 to 6 of 6 rows
Gene-Drug: Aster Plot
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in XPO5
Loading, please wait...
Model | Level | Reference ID | Tissue | Cancer | Drug | Clinical Response | Source | |
|---|---|---|---|---|---|---|---|---|
| No matching records found | ||||||||
CLASSFICATION
Copyright © 2018 Modellab | All Rights Reserved
Disclaimer: iGMDR is intended for research purposes only. Its information cannot be used for emergencies or medical or professional advice.