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STK17A

Summary: This gene is a member of the DAP kinase-related apoptosis-inducing protein kinase family and encodes an autophosphorylated nuclear protein with a protein kinase domain. The protein has apoptosis-inducing activity. [provided by RefSeq, Jul 2008].

Name	OMIM ID	Ensembl ID	HGNC ID	PHARMGKB ID	Map Location
serine/threonine kinase 17a	MIM:604726	Ensembl:ENSG00000164543	HGNC:HGNC:11395	PA36203	7p13

Gene Categories:

KINASE SERINE THREONINE KINASE DRUGGABLE GENOME

GO terms in STK17A

Term Type	Evidence Type	GO Term ID	GO Des.
MF	IBA	GO:0004674	protein serine/threonine kinase activity
MF	IDA	GO:0004674	protein serine/threonine kinase activity
MF	IBA	GO:0005524	ATP binding
MF	IDA	GO:0005524	ATP binding
BP	IDA	GO:0006468	protein phosphorylation
BP	IEA	GO:0006915	apoptotic process
BP	IDA	GO:0035556	intracellular signal transduction
BP	IMP	GO:0043065	positive regulation of apoptotic process
BP	IMP	GO:2000271	positive regulation of fibroblast apoptotic process
BP	IMP	GO:2000377	regulation of reactive oxygen species metabolic process
CC	IBA	GO:0005634	nucleus
CC	IDA	GO:0005634	nucleus
CC	IDA	GO:0005886	plasma membrane
CC	IDA	GO:0016607	nuclear speck

Gene expression in normal tissue: STK17A

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Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in STK17A

Database	Pathway ID	Pathway Des.

Gene-Drug: Aster Plot

Drug ID	Drug Name	Model Num.
iGMDRD210	AC55649	1
iGMDRD126	Tipifarnib	2
iGMDRD318	PAC-1	1
iGMDRD434	BMS-536924	2
iGMDRD289	Parthenolide	1
iGMDRD105	Triptolide	3
iGMDRD577	BIX01294	1
iGMDRD506	Fedratinib	1
iGMDRD945	ML214	6

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in STK17A

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DATATYPES

CLASSFICATION

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