SCYL3


Summary: This gene encodes a protein with a kinase domain and four HEAT repeats. The encoded protein interacts with the C-terminal domain of ezrin, an ERM protein, and may play a role in cell adhesion and migration. Alternative splicing results in multiple transcript variants encoding multiple isoforms. [provided by RefSeq, Jun 2012].

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GO terms in SCYL3


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Term Type
Evidence Type
GO Term ID
GO Des.
MF IPI GO:0005515 protein binding
MF IEA GO:0005524 ATP binding
MF IDA GO:0016301 kinase activity
BP IEA GO:0006468 protein phosphorylation
BP NAS GO:0016477 cell migration
CC IDA GO:0005737 cytoplasm
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Gene expression in normal tissue: SCYL3

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

undefined20Leukocyte transendothelial migration1Apoptosis regulation1Longevity regulating pathway1PI3K/MTOR signaling1Mitosis1

Pathways in SCYL3


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Database
Pathway ID
Pathway Des.
No matching records found

Gene-Drug: Aster Plot


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Drug ID
Drug Name
Model Num.
iGMDRD297 Austocystin D 2
iGMDRD280 CYTOCHALASIN B 2
iGMDRD679 Bistramide A 1
iGMDRD123 Isoevodiamine 2
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Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in SCYL3

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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