HOXA11
Summary: In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. This gene is involved in the regulation of uterine development and is required for female fertility. Mutations in this gene can cause radio-ulnar synostosis with amegakaryocytic thrombocytopenia. [provided by RefSeq, Jul 2008].
Loading, please wait...
Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
---|---|---|---|---|---|
Namehomeobox A11 OMIM IDMIM:142958 Ensembl IDEnsembl:ENSG00000005073 HGNC IDHGNC:HGNC:5101 PHARMGKB IDPA29378 Map Location7p15.2 |
Gene Categories:
TRANSCRIPTION FACTOR COMPLEXGO terms in HOXA11
Loading, please wait...
Term Type | Evidence Type | GO Term ID | GO Des. |
---|---|---|---|
CC | IDA | GO:0005654 | nucleoplasm |
CC | ISS | GO:0005667 | transcription factor complex |
CC | ISS | GO:0032991 | protein-containing complex |
CC | ISS | GO:0032993 | protein-DNA complex |
BP | ISS | GO:0001501 | skeletal system development |
BP | IEA | GO:0001656 | metanephros development |
Gene expression in normal tissue: HOXA11
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in HOXA11
Loading, please wait...
Database | Pathway ID | Pathway Des. |
---|---|---|
kegg | hsa05202 | Transcriptional misregulation in cancer - Homo sapiens (human) |
Showing 1 to 1 of 1 rows
Gene-Drug: Aster Plot
Gene in drug-gene network: Network Plot

Gene-drug targets distribution
Gene Structure: PDB
Models in HOXA11
Loading, please wait...
Model | Level | Reference ID | Tissue | Cancer | Drug | Clinical Response | Source | |
---|---|---|---|---|---|---|---|---|
No matching records found |