TPPP
Summary:
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| tubulin polymerization promoting protein | MIM:608773 | Ensembl:ENSG00000171368 | HGNC:HGNC:24164 | PA162406809 | 5p15.33 |
GO terms in TPPP
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| MF | IPI | GO:0005515 | protein binding |
| MF | ISS | GO:0008017 | microtubule binding |
| MF | IBA | GO:0015631 | tubulin binding |
| MF | IDA | GO:0015631 | tubulin binding |
| MF | ISS | GO:0015631 | tubulin binding |
| BP | IBA | GO:0001578 | microtubule bundle formation |
| BP | IDA | GO:0001578 | microtubule bundle formation |
| BP | ISS | GO:0001578 | microtubule bundle formation |
| BP | ISS | GO:0031334 | positive regulation of protein complex assembly |
| BP | IBA | GO:0032273 | positive regulation of protein polymerization |
| BP | IDA | GO:0032273 | positive regulation of protein polymerization |
| BP | IBA | GO:0046785 | microtubule polymerization |
| BP | IDA | GO:0046785 | microtubule polymerization |
| BP | ISS | GO:0046785 | microtubule polymerization |
| CC | IDA | GO:0005634 | nucleus |
| CC | IDA | GO:0005737 | cytoplasm |
| CC | IDA | GO:0005739 | mitochondrion |
| CC | IDA | GO:0005829 | cytosol |
| CC | IBA | GO:0005874 | microtubule |
| CC | IDA | GO:0005874 | microtubule |
| CC | IEA | GO:0043209 | myelin sheath |
| CC | IDA | GO:0048471 | perinuclear region of cytoplasm |
| CC | IDA | GO:0097427 | microtubule bundle |
Gene expression in normal tissue: TPPP
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in TPPP
| Database | Pathway ID | Pathway Des. |
|---|---|---|
| wikipathways | WP2038 | Regulation of Microtubule Cytoskeleton |
| wikipathways | WP2276 | Glial Cell Differentiation |
| wikipathways | WP706 | Sudden Infant Death Syndrome (SIDS) Susceptibility Pathways |
Gene-Drug: Aster Plot
| Drug ID | Drug Name | Model Num. |
|---|---|---|
| iGMDRD885 | Compound 110 | 3 |
| iGMDRD105 | Triptolide | 2 |
| iGMDRD137 | Indisulam | 3 |
| iGMDRD121 | GMX1778 | 2 |
| iGMDRD147 | Prima-1 | 1 |
| iGMDRD369 | TGX-115 | 2 |
| iGMDRD300 | Tozasertib | 5 |
| iGMDRD398 | Sepantronium | 2 |
| iGMDRD562 | Navitoclax | 3 |
| iGMDRD577 | BIX01294 | 1 |
| iGMDRD329 | Merck60 | 3 |
| iGMDRD286 | Nsc 632839 | 8 |
| iGMDRD188 | Piperlongumine | 2 |
| iGMDRD367 | Ro 28-1675 | 3 |
| iGMDRD100 | Zebularine | 1 |
| iGMDRD781 | Sirolimus | 5 |
| iGMDRD144 | NSC95397 | 2 |
| iGMDRD772 | BRD4770 | 1 |
| iGMDRD579 | PF750 | 3 |
| iGMDRD512 | nutlin 3 | 4 |
| iGMDRD210 | AC55649 | 1 |
| iGMDRD126 | Tipifarnib | 3 |
| iGMDRD154 | NSC23766 | 2 |
| iGMDRD945 | ML214 | 2 |
| iGMDRD634 | SCHEMBL2608041 | 3 |
| iGMDRD152 | 179324-69-7 | 1 |
| iGMDRD61 | Kinetin riboside | 2 |
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in TPPP
CLASSFICATION
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