NEK5

Summary:

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Name
OMIM ID
Ensembl ID
HGNC ID
PHARMGKB ID
Map Location
NameNIMA related kinase 5
OMIM IDMIM:616731
Ensembl IDEnsembl:ENSG00000197168
HGNC IDHGNC:HGNC:7748
PHARMGKB IDPA31549
Map Location13q14.3

GO terms in NEK5


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Term Type
Evidence Type
GO Term ID
GO Des.
MF IEA GO:0004674 protein serine/threonine kinase activity
MF IEA GO:0005524 ATP binding
MF IEA GO:0046872 metal ion binding
BP IEA GO:0006468 protein phosphorylation
BP IEA GO:0051155 positive regulation of striated muscle cell differentiation
BP IEA GO:2001056 positive regulation of cysteine-type endopeptidase activity
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Gene expression in normal tissue: NEK5

16 tissues mixtureadiposeadrenalbrainbreastcolonheartkidneyliverlunglymph nodeovaryprostateskeletal muscletestesthyroidwhite blood cells

Gene-model tissue-cancer distribution: Bubble Plot

undefinetissue: undefine cancer: undefined model num: 0undefinedtissue: undefined cancer: PANCAN model num: 53undefinedtissue: undefined cancer: ADENOCARCINOMA model num: 3BOWEtissue: BOWE cancer: BOWEL model num: 0BOWELtissue: BOWEL cancer: undefined model num: 12UTERUtissue: UTERU cancer: UTERUS model num: 0UTERUStissue: UTERUS cancer: Endometrial Carcinoma (UCEC) model num: 6LUNtissue: LUN cancer: LUNG model num: 0LUNGtissue: LUNG cancer: undefined model num: 3

Gene-drug pathway distribution

undefined22Apoptosis regulation2One carbon pool by folate1WNT signaling1ERK MAPK signaling1ABL signaling1DNA replication1Ferroptosis1PI3K/MTOR signaling1Other, kinases1

Pathways in NEK5


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Database
Pathway ID
Pathway Des.
No matching records found

Gene-Drug: Aster Plot


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Drug ID
Drug Name
Model Num.
iGMDRD246 NPC26 2
iGMDRD329 Merck60 1
iGMDRD105 Triptolide 2
iGMDRD271 Brefeldin A 2
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Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in NEK5

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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