TLE1

Summary:

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Name
OMIM ID
Ensembl ID
HGNC ID
PHARMGKB ID
Map Location
Nametransducin like enhancer of split 1
OMIM IDMIM:600189
Ensembl IDEnsembl:ENSG00000196781
HGNC IDHGNC:HGNC:11837
PHARMGKB IDPA36539
Map Location9q21.32

GO terms in TLE1


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Term Type
Evidence Type
GO Term ID
GO Des.
CC IBA GO:0005634 nucleus
CC IDA GO:0005634 nucleus
CC IMP GO:0005634 nucleus
CC IDA GO:0005654 nucleoplasm
CC TAS GO:0005654 nucleoplasm
CC IBA GO:0005667 transcription factor complex
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Gene expression in normal tissue: TLE1

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in TLE1


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Database
Pathway ID
Pathway Des.
reactome R-HSA-157118 Signaling by NOTCH
reactome R-HSA-162582 Signal Transduction
reactome R-HSA-162582 Signal Transduction
reactome R-HSA-195253 Degradation of beta-catenin by the destruction complex
reactome R-HSA-195253 Degradation of beta-catenin by the destruction complex
reactome R-HSA-195721 Signaling by WNT
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Gene-Drug: Aster Plot


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Drug ID
Drug Name
Model Num.
iGMDRD494 Neopeltolide 2
iGMDRD523 Cyanoquinoline, 11 2
iGMDRD405 PIK-75 3
iGMDRD345 Compound 10b [PMID: 11504634] 2
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Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in TLE1

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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