CDK20
Summary: The protein encoded by this gene contains a kinase domain most closely related to the cyclin-dependent protein kinases. The encoded kinase may activate cyclin-dependent kinase 2 and is involved in cell growth. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Dec 2009].
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| cyclin dependent kinase 20 | MIM:610076 | Ensembl:ENSG00000156345 | HGNC:HGNC:21420 | PA165585688 | 9q22.1 |
GO terms in CDK20
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| CC | IBA | GO:0005634 | nucleus |
| CC | IDA | GO:0005654 | nucleoplasm |
| CC | IEA | GO:0005929 | cilium |
| BP | IBA | GO:0006468 | protein phosphorylation |
| BP | IEA | GO:0006468 | protein phosphorylation |
| BP | IEA | GO:0007049 | cell cycle |
| BP | IEA | GO:0007275 | multicellular organism development |
| BP | IEA | GO:0051301 | cell division |
| MF | IBA | GO:0004693 | cyclin-dependent protein serine/threonine kinase activity |
| MF | IPI | GO:0005515 | protein binding |
| MF | IEA | GO:0005524 | ATP binding |
| MF | IBA | GO:0019912 | cyclin-dependent protein kinase activating kinase activity |
Gene expression in normal tissue: CDK20
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in CDK20
| Database | Pathway ID | Pathway Des. |
|---|
Gene-Drug: Aster Plot
| Drug ID | Drug Name | Model Num. |
|---|---|---|
| iGMDRD237 | ABT-751 | 3 |
| iGMDRD154 | NSC23766 | 2 |
| iGMDRD132 | (-)-gallocatechin-3-O-gallate | 6 |
| iGMDRD466 | Chaetocin | 1 |
| iGMDRD387 | CHIR-99021 | 2 |
| iGMDRD1008 | SR-II-138A | 2 |
| iGMDRD523 | Cyanoquinoline, 11 | 1 |
| iGMDRD79 | Gemcitabine | 2 |
| iGMDRD144 | NSC95397 | 2 |
| iGMDRD427 | ABT737 | 1 |
| iGMDRD67 | PENFLURIDOL | 3 |
| iGMDRD414 | MST-312 | 3 |
| iGMDRD882 | CIL41 | 2 |
| iGMDRD268 | Cerulenin | 3 |
| iGMDRD690 | PRIMA-1MET | 2 |
| iGMDRD60 | Quinoclamine | 2 |
| iGMDRD137 | Indisulam | 2 |
| iGMDRD6 | AM-580 | 3 |
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in CDK20
CLASSFICATION
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