EPPK1
Summary: The protein encoded by this gene belongs to the plakin family of proteins, which play a role in the organization of cytoskeletal architecture. This family member is composed of several highly homologous plakin repeats. It may function to maintain the integrity of keratin intermediate filament networks in epithelial cells. Studies of the orthologous mouse protein suggest that it accelerates keratinocyte migration during wound healing. [provided by RefSeq, Oct 2013].
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Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
Nameepiplakin 1 OMIM IDMIM:607553 Ensembl IDEnsembl:ENSG00000261150 HGNC IDHGNC:HGNC:15577 PHARMGKB IDPA27835 Map Location8q24.3 | |||||
GO terms in EPPK1
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Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| MF | HDA | GO:0003723 | RNA binding |
| MF | IBA | GO:0005198 | structural molecule activity |
| MF | IEA | GO:0008092 | cytoskeletal protein binding |
| MF | IPI | GO:0019215 | intermediate filament binding |
| MF | IBA | GO:0045296 | cadherin binding |
| MF | IBA | GO:1990254 | keratin filament binding |
Gene expression in normal tissue: EPPK1
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in EPPK1
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Database | Pathway ID | Pathway Des. |
|---|---|---|
| netpath | Pathway_EGFR1 | EGFR1 |
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Gene-Drug: Aster Plot
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in EPPK1
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Model | Level | Reference ID | Tissue | Cancer | Drug | Clinical Response | Source | |
|---|---|---|---|---|---|---|---|---|
| No matching records found | ||||||||
CLASSFICATION
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