OSR1
Summary:
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| odd-skipped related transciption factor 1 | MIM:608891 | Ensembl:ENSG00000143867 | HGNC:HGNC:8111 | PA164742217 | 2p24.1 |
GO terms in OSR1
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| MF | ISA | GO:0000981 | RNA polymerase II transcription factor activity, sequence-specific DNA binding |
| MF | IEA | GO:0003676 | nucleic acid binding |
| MF | IMP | GO:0004674 | protein serine/threonine kinase activity |
| MF | IPI | GO:0005515 | protein binding |
| MF | IPI | GO:0019901 | protein kinase binding |
| MF | IEA | GO:0046872 | metal ion binding |
| BP | ISS | GO:0000122 | negative regulation of transcription by RNA polymerase II |
| BP | ISS | GO:0001655 | urogenital system development |
| BP | ISS | GO:0001657 | ureteric bud development |
| BP | ISS | GO:0001823 | mesonephros development |
| BP | ISS | GO:0002062 | chondrocyte differentiation |
| BP | IEA | GO:0006351 | transcription, DNA-templated |
| BP | IMP | GO:0007231 | osmosensory signaling pathway |
| BP | ISS | GO:0007507 | heart development |
| BP | IEA | GO:0008406 | gonad development |
| BP | ISS | GO:0010628 | positive regulation of gene expression |
| BP | IMP | GO:0018107 | peptidyl-threonine phosphorylation |
| BP | IMP | GO:0023016 | signal transduction by trans-phosphorylation |
| BP | ISS | GO:0030154 | cell differentiation |
| BP | ISS | GO:0030501 | positive regulation of bone mineralization |
| BP | ISS | GO:0030857 | negative regulation of epithelial cell differentiation |
| BP | ISS | GO:0035115 | embryonic forelimb morphogenesis |
| BP | ISS | GO:0035116 | embryonic hindlimb morphogenesis |
| BP | ISS | GO:0036023 | embryonic skeletal limb joint morphogenesis |
| BP | ISS | GO:0042474 | middle ear morphogenesis |
| BP | ISS | GO:0042476 | odontogenesis |
| BP | ISS | GO:0042733 | embryonic digit morphogenesis |
| BP | ISS | GO:0043066 | negative regulation of apoptotic process |
| BP | ISS | GO:0045944 | positive regulation of transcription by RNA polymerase II |
| BP | IEA | GO:0048389 | intermediate mesoderm development |
| BP | IMP | GO:0048793 | pronephros development |
| BP | ISS | GO:0048863 | stem cell differentiation |
| BP | ISS | GO:0050679 | positive regulation of epithelial cell proliferation |
| BP | ISS | GO:0060021 | roof of mouth development |
| BP | ISS | GO:0060272 | embryonic skeletal joint morphogenesis |
| BP | IEA | GO:0071300 | cellular response to retinoic acid |
| BP | ISS | GO:0072075 | metanephric mesenchyme development |
| BP | ISS | GO:0072111 | cell proliferation involved in kidney development |
| BP | ISS | GO:0072133 | metanephric mesenchyme morphogenesis |
| BP | ISS | GO:0072143 | mesangial cell development |
| BP | ISS | GO:0072162 | metanephric mesenchymal cell differentiation |
| BP | ISS | GO:0072166 | posterior mesonephric tubule development |
| BP | ISS | GO:0072168 | specification of anterior mesonephric tubule identity |
| BP | ISS | GO:0072169 | specification of posterior mesonephric tubule identity |
| BP | ISS | GO:0072180 | mesonephric duct morphogenesis |
| BP | ISS | GO:0072183 | negative regulation of nephron tubule epithelial cell differentiation |
| BP | ISS | GO:0072184 | renal vesicle progenitor cell differentiation |
| BP | ISS | GO:0072190 | ureter urothelium development |
| BP | ISS | GO:0072207 | metanephric epithelium development |
| BP | ISS | GO:0072208 | metanephric smooth muscle tissue development |
| BP | ISS | GO:0072234 | metanephric nephron tubule development |
| BP | ISS | GO:0072239 | metanephric glomerulus vasculature development |
| BP | ISS | GO:0072259 | metanephric interstitial fibroblast development |
| BP | ISS | GO:0072268 | pattern specification involved in metanephros development |
| BP | ISS | GO:0072498 | embryonic skeletal joint development |
| BP | ISS | GO:0090094 | metanephric cap mesenchymal cell proliferation involved in metanephros development |
| BP | IDA | GO:1905408 | negative regulation of creatine transmembrane transporter activity |
| BP | IMP | GO:2000543 | positive regulation of gastrulation |
| BP | IDA | GO:2000650 | negative regulation of sodium ion transmembrane transporter activity |
| CC | IDA | GO:0005634 | nucleus |
| CC | ISS | GO:0005829 | cytosol |
| CC | ISS | GO:0019898 | extrinsic component of membrane |
Gene expression in normal tissue: OSR1
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in OSR1
| Database | Pathway ID | Pathway Des. |
|---|
Gene-Drug: Aster Plot
| Drug ID | Drug Name | Model Num. |
|---|---|---|
| iGMDRD375 | GW-405833 | 3 |
| iGMDRD883 | CIL55A | 1 |
| iGMDRD394 | BX-795 | 6 |
| iGMDRD193 | Fqi1 | 1 |
| iGMDRD152 | 179324-69-7 | 3 |
| iGMDRD446 | LY 2183240 | 1 |
| iGMDRD483 | SCH-529074 | 3 |
| iGMDRD345 | Compound 10b [PMID: 11504634] | 3 |
| iGMDRD1008 | SR-II-138A | 4 |
| iGMDRD330 | BRD4132 | 3 |
| iGMDRD307 | Manumycin A | 3 |
| iGMDRD554 | CHEMBL1434137 | 3 |
| iGMDRD82 | Quiflapon | 6 |
| iGMDRD300 | Tozasertib | 1 |
| iGMDRD64 | Parbendazole | 3 |
| iGMDRD60 | Quinoclamine | 3 |
| iGMDRD506 | Fedratinib | 1 |
| iGMDRD871 | BRD6368 | 3 |
| iGMDRD52 | Rotenone | 3 |
| iGMDRD77 | Itraconazole | 3 |
| iGMDRD6 | AM-580 | 3 |
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in OSR1
CLASSFICATION
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