TAF1L

Summary: This locus is intronless, and apparently arose in the primate lineage from retrotransposition of the transcript from the multi-exon TAF1 locus on the X chromosome. The gene is expressed in male germ cells, and the product has been shown to function interchangeably with the TAF1 product. [provided by RefSeq, Aug 2015].

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Name
OMIM ID
Ensembl ID
HGNC ID
PHARMGKB ID
Map Location
NameTATA-box binding protein associated factor 1 like
OMIM IDMIM:607798
Ensembl IDEnsembl:ENSG00000122728
HGNC IDHGNC:HGNC:18056
PHARMGKB IDPA134947802
Map Location9p21.1

GO terms in TAF1L


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Term Type
Evidence Type
GO Term ID
GO Des.
MF ISA GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding
MF IBA GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly
MF IBA GO:0001129 RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly
MF IBA GO:0004402 histone acetyltransferase activity
MF ISS GO:0004402 histone acetyltransferase activity
MF ISS GO:0004674 protein serine/threonine kinase activity
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Gene expression in normal tissue: TAF1L

Gene-model tissue-cancer distribution: Bubble Plot

undefinetissue: undefine cancer: undefined model num: 0undefinedtissue: undefined cancer: PANCAN model num: 15undefinedtissue: undefined cancer: ADENOCARCINOMA model num: 3BOWEtissue: BOWE cancer: BOWEL model num: 0BOWELtissue: BOWEL cancer: undefined model num: 8LUNtissue: LUN cancer: LUNG model num: 0LUNGtissue: LUNG cancer: undefined model num: 3OVARtissue: OVAR cancer: OVARY model num: 0OVARYtissue: OVARY cancer: undefined model num: 6UTERUtissue: UTERU cancer: UTERUS model num: 0UTERUStissue: UTERUS cancer: Endometrial Carcinoma (UCEC) model num: 3BLOOtissue: BLOO cancer: BLOOD model num: 0BLOODtissue: BLOOD cancer: undefined model num: 3

Gene-drug pathway distribution

undefined10RTK signaling1Chromatin histone acetylation1DNA replication1

Pathways in TAF1L


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Database
Pathway ID
Pathway Des.
reactome R-HSA-162587 HIV Life Cycle
reactome R-HSA-162599 Late Phase of HIV Life Cycle
reactome R-HSA-162906 HIV Infection
reactome R-HSA-1643685 Disease
reactome R-HSA-167161 HIV Transcription Initiation
reactome R-HSA-167162 RNA Polymerase II HIV Promoter Escape
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Gene-Drug: Aster Plot


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Drug ID
Drug Name
Model Num.
iGMDRD405 PIK-75 2
iGMDRD483 SCH-529074 3
iGMDRD434 BMS-536924 2
iGMDRD424 Tamatinib 3
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Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in TAF1L

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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