NRBP1
Summary:
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| nuclear receptor binding protein 1 | MIM:606010 | Ensembl:ENSG00000115216 | HGNC:HGNC:7993 | PA31772 | 2p23.3 |
GO terms in NRBP1
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| MF | IBA | GO:0004674 | protein serine/threonine kinase activity |
| MF | IPI | GO:0005515 | protein binding |
| MF | IEA | GO:0005524 | ATP binding |
| MF | ISS | GO:0042803 | protein homodimerization activity |
| CC | TAS | GO:0005654 | nucleoplasm |
| CC | IBA | GO:0005829 | cytosol |
| CC | IEA | GO:0005938 | cell cortex |
| CC | IBA | GO:0012505 | endomembrane system |
| CC | IDA | GO:0012505 | endomembrane system |
| CC | IEA | GO:0016020 | membrane |
| CC | IEA | GO:0030027 | lamellipodium |
| BP | TAS | GO:0006367 | transcription initiation from RNA polymerase II promoter |
| BP | IBA | GO:0006468 | protein phosphorylation |
| BP | IBA | GO:0006888 | ER to Golgi vesicle-mediated transport |
| BP | IDA | GO:0006888 | ER to Golgi vesicle-mediated transport |
| BP | IBA | GO:0035556 | intracellular signal transduction |
Gene expression in normal tissue: NRBP1
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in NRBP1
| Database | Pathway ID | Pathway Des. |
|---|---|---|
| reactome | R-HSA-212436 | Generic Transcription Pathway |
| reactome | R-HSA-383280 | Nuclear Receptor transcription pathway |
| reactome | R-HSA-73857 | RNA Polymerase II Transcription |
| reactome | R-HSA-74160 | Gene expression (Transcription) |
Gene-Drug: Aster Plot
| Drug ID | Drug Name | Model Num. |
|---|---|---|
| iGMDRD398 | Sepantronium | 3 |
| iGMDRD577 | BIX01294 | 4 |
| iGMDRD888 | Compound 44 | 1 |
| iGMDRD74 | Idarubicin | 2 |
| iGMDRD367 | Ro 28-1675 | 2 |
| iGMDRD100 | Zebularine | 5 |
| iGMDRD524 | ISX-9 | 2 |
| iGMDRD322 | FK 866 | 2 |
| iGMDRD82 | Quiflapon | 2 |
| iGMDRD356 | PNU-74654 | 2 |
| iGMDRD64 | Parbendazole | 1 |
| iGMDRD121 | GMX1778 | 2 |
| iGMDRD513 | BML-259 | 2 |
| iGMDRD294 | Batimastat | 1 |
| iGMDRD213 | SMR000068650 | 2 |
| iGMDRD52 | Rotenone | 2 |
| iGMDRD193 | Fqi1 | 2 |
| iGMDRD316 | N9-Isopropyl-olomoucine | 2 |
| iGMDRD201 | SKI II | 1 |
| iGMDRD446 | LY 2183240 | 2 |
| iGMDRD280 | CYTOCHALASIN B | 2 |
| iGMDRD466 | Chaetocin | 2 |
| iGMDRD1008 | SR-II-138A | 2 |
| iGMDRD579 | PF750 | 3 |
| iGMDRD345 | Compound 10b [PMID: 11504634] | 2 |
| iGMDRD427 | ABT737 | 3 |
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in NRBP1
CLASSFICATION
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