TRIM36


Summary: The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. Multiple alternatively spliced transcript variants that encode different protein isoforms have been described for this gene. [provided by RefSeq, Jul 2008].

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Name
OMIM ID
Ensembl ID
HGNC ID
PHARMGKB ID
Map Location

GO terms in TRIM36


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Term Type
Evidence Type
GO Term ID
GO Des.
MF EXP GO:0004842 ubiquitin-protein transferase activity
MF ISS GO:0004842 ubiquitin-protein transferase activity
MF TAS GO:0004842 ubiquitin-protein transferase activity
MF IPI GO:0005515 protein binding
MF IEA GO:0008270 zinc ion binding
MF ISS GO:0043014 alpha-tubulin binding
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Gene expression in normal tissue: TRIM36

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

undefined24ERK MAPK signaling2Protein stability and degradation1Other, kinases1Stilbenoid, diarylheptanoid and gingerol biosynthesis1Purine metabolism1DNA replication1

Pathways in TRIM36


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Database
Pathway ID
Pathway Des.
reactome R-HSA-1280218 Adaptive Immune System
reactome R-HSA-168256 Immune System
reactome R-HSA-983168 Antigen processing: Ubiquitination & Proteasome degradation
reactome R-HSA-983169 Class I MHC mediated antigen processing & presentation
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Gene-Drug: Aster Plot


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Drug ID
Drug Name
Model Num.
iGMDRD512 nutlin 3 3
iGMDRD1008 SR-II-138A 3
iGMDRD433 Lexibulin 3
iGMDRD307 Manumycin A 3
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Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in TRIM36

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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