IL17RD


Summary: This gene encodes a membrane protein belonging to the interleukin-17 receptor (IL-17R) protein family. The encoded protein is a component of the interleukin-17 receptor signaling complex, and the interaction between this protein and IL-17R does not require the interleukin. The gene product also affects fibroblast growth factor signaling, inhibiting or stimulating growth through MAPK/ERK signaling. Alternate splicing generates multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jan 2016].

NameOMIM IDEnsembl IDHGNC IDPHARMGKB IDMap Location
interleukin 17 receptor DMIM:606807Ensembl:ENSG00000144730HGNC:HGNC:17616PA1349934073p14.3

GO terms in IL17RD


Term TypeEvidence TypeGO Term IDGO Des.
CCTASGO:0000139Golgi membrane
CCIDAGO:0005654nucleoplasm
CCIDAGO:0005794Golgi apparatus
BPTASGO:0000165MAPK cascade
BPIEAGO:0019221cytokine-mediated signaling pathway
MFIBAGO:0030368interleukin-17 receptor activity

Gene expression in normal tissue: IL17RD

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in IL17RD


DatabasePathway IDPathway Des.
netpathPathway_EGFR1EGFR1
pidfgf_pathwayFGF signaling pathway
wikipathwaysWP2112IL17 signaling pathway
wikipathwaysWP3651Pathways Affected in Adenoid Cystic Carcinoma
reactomeR-HSA-162582Signal Transduction
reactomeR-HSA-5673001RAF/MAP kinase cascade
reactomeR-HSA-5674135MAP2K and MAPK activation
reactomeR-HSA-5683057MAPK family signaling cascades
reactomeR-HSA-5684996MAPK1/MAPK3 signaling

Gene-Drug: Aster Plot


Drug IDDrug NameModel Num.
iGMDRD639YK 4-2793
iGMDRD193Fqi13
iGMDRD446LY 21832403
iGMDRD297Austocystin D6
iGMDRD211(1S,3R)-RSL34
iGMDRD123Isoevodiamine6
iGMDRD584VER 1550082
iGMDRD151CHM-13
iGMDRD433Lexibulin3
iGMDRD670ML 2105
iGMDRD888Compound 446
iGMDRD780PP-302
iGMDRD366PI-1034
iGMDRD871BRD63685
iGMDRD246NPC263
iGMDRD60Quinoclamine5
iGMDRD64Parbendazole9
iGMDRD260FQI-21

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in IL17RD

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