ICAM1
Summary: This gene encodes a cell surface glycoprotein which is typically expressed on endothelial cells and cells of the immune system. It binds to integrins of type CD11a / CD18, or CD11b / CD18 and is also exploited by Rhinovirus as a receptor. [provided by RefSeq, Jul 2008].
Loading, please wait...
Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
---|---|---|---|---|---|
OMIM IDMIM:147840 Ensembl IDEnsembl:ENSG00000090339 HGNC IDHGNC:HGNC:5344 PHARMGKB IDPA29592 Map Location19p13.2 |
GO terms in ICAM1
Loading, please wait...
Term Type | Evidence Type | GO Term ID | GO Des. |
---|---|---|---|
MF | IEA | GO:0001618 | virus receptor activity |
MF | TAS | GO:0004888 | transmembrane signaling receptor activity |
MF | IBA | GO:0005178 | integrin binding |
MF | IDA | GO:0005178 | integrin binding |
MF | IPI | GO:0005178 | integrin binding |
MF | IPI | GO:0005515 | protein binding |
Gene expression in normal tissue: ICAM1
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in ICAM1
Loading, please wait...
Database | Pathway ID | Pathway Des. |
---|---|---|
reactome | R-HSA-1280215 | Cytokine Signaling in Immune system |
reactome | R-HSA-1280218 | Adaptive Immune System |
reactome | R-HSA-1474244 | Extracellular matrix organization |
reactome | R-HSA-168256 | Immune System |
reactome | R-HSA-198933 | Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell |
reactome | R-HSA-216083 | Integrin cell surface interactions |
Gene-Drug: Aster Plot
Gene in drug-gene network: Network Plot

Gene-drug targets distribution
Gene Structure: PDB
Models in ICAM1
Loading, please wait...
Model | Level | Reference ID | Tissue | Cancer | Drug | Clinical Response | Source | |
---|---|---|---|---|---|---|---|---|
No matching records found |