NUAK1

Summary:

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Name
OMIM ID
Ensembl ID
HGNC ID
PHARMGKB ID
Map Location
NameNUAK family kinase 1
OMIM IDMIM:608130
Ensembl IDEnsembl:ENSG00000074590
HGNC IDHGNC:HGNC:14311
PHARMGKB IDPA142671242
Map Location12q23.3

GO terms in NUAK1


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Term Type
Evidence Type
GO Term ID
GO Des.
MF IPI GO:0002039 p53 binding
MF IBA GO:0004674 protein serine/threonine kinase activity
MF IDA GO:0004674 protein serine/threonine kinase activity
MF TAS GO:0004674 protein serine/threonine kinase activity
MF IBA GO:0004679 AMP-activated protein kinase activity
MF IPI GO:0005515 protein binding
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Gene expression in normal tissue: NUAK1

16 tissues mixtureadiposeadrenalbrainbreastcolonheartkidneyliverlunglymph nodeovaryprostateskeletal muscletestesthyroidwhite blood cells

Gene-model tissue-cancer distribution: Bubble Plot

undefinetissue: undefine cancer: undefined model num: 0undefinedtissue: undefined cancer: PANCAN model num: 28undefinedtissue: undefined cancer: NON_SMALL_CELL_CARCINOMA model num: 2undefinedtissue: undefined cancer: ADENOCARCINOMA model num: 3LUNtissue: LUN cancer: LUNG model num: 0LUNGtissue: LUNG cancer: undefined model num: 10BOWEtissue: BOWE cancer: BOWEL model num: 0BOWELtissue: BOWEL cancer: undefined model num: 3

Gene-drug pathway distribution

undefined15Ferroptosis1Apoptosis regulation1

Pathways in NUAK1


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Database
Pathway ID
Pathway Des.
reactome R-HSA-212436 Generic Transcription Pathway
reactome R-HSA-3700989 Transcriptional Regulation by TP53
reactome R-HSA-5633007 Regulation of TP53 Activity
reactome R-HSA-6804756 Regulation of TP53 Activity through Phosphorylation
reactome R-HSA-73857 RNA Polymerase II Transcription
reactome R-HSA-74160 Gene expression (Transcription)
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Gene-Drug: Aster Plot


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Drug ID
Drug Name
Model Num.
iGMDRD441 TW 37 1
iGMDRD77 Itraconazole 2
iGMDRD105 Triptolide 5
iGMDRD6 AM-580 3
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Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in NUAK1

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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