GO terms in NUAK1


Term TypeEvidence TypeGO Term IDGO Des.
MFIPIGO:0002039p53 binding
MFIBAGO:0004674protein serine/threonine kinase activity
MFIDAGO:0004674protein serine/threonine kinase activity
MFTASGO:0004674protein serine/threonine kinase activity
MFIBAGO:0004679AMP-activated protein kinase activity
MFIPIGO:0005515protein binding
MFIEAGO:0005524ATP binding
MFIBAGO:0035174histone serine kinase activity
MFIEAGO:0046872metal ion binding
BPIBAGO:0006468protein phosphorylation
BPIDAGO:0006468protein phosphorylation
BPIEAGO:0006974cellular response to DNA damage stimulus
BPIEAGO:0007155cell adhesion
BPIDAGO:0030155regulation of cell adhesion
BPIDAGO:0035507regulation of myosin-light-chain-phosphatase activity
BPIBAGO:0035556intracellular signal transduction
BPTASGO:0042127regulation of cell proliferation
BPTASGO:1901796regulation of signal transduction by p53 class mediator
BPIDAGO:2000772regulation of cellular senescence
CCIDAGO:0001650fibrillar center
CCIBAGO:0005634nucleus
CCIDAGO:0005634nucleus
CCTASGO:0005654nucleoplasm
CCIBAGO:0005737cytoplasm
CCIDAGO:0005737cytoplasm
CCIDAGO:0015630microtubule cytoskeleton

Gene expression in normal tissue: NUAK1

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in NUAK1


DatabasePathway IDPathway Des.
reactomeR-HSA-212436Generic Transcription Pathway
reactomeR-HSA-3700989Transcriptional Regulation by TP53
reactomeR-HSA-5633007Regulation of TP53 Activity
reactomeR-HSA-6804756Regulation of TP53 Activity through Phosphorylation
reactomeR-HSA-73857RNA Polymerase II Transcription
reactomeR-HSA-74160Gene expression (Transcription)

Gene-Drug: Aster Plot


Drug IDDrug NameModel Num.
iGMDRD441TW 371
iGMDRD77Itraconazole2
iGMDRD105Triptolide5
iGMDRD6AM-5803
iGMDRD474Avrainvillamide2
iGMDRD505Pevonedistat3
iGMDRD60Quinoclamine4
iGMDRD369TGX-1153
iGMDRD188Piperlongumine2
iGMDRD286Nsc 6328393
iGMDRD367Ro 28-16753
iGMDRD779PRL-3 Inhibitor I3
iGMDRD579PF7503
iGMDRD211(1S,3R)-RSL33
iGMDRD466Chaetocin1
iGMDRD280CYTOCHALASIN B3
iGMDRD446LY 21832402

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in NUAK1

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