CDC34
Summary: The protein encoded by this gene is a member of the ubiquitin-conjugating enzyme family. Ubiquitin-conjugating enzyme catalyzes the covalent attachment of ubiquitin to other proteins. This protein is a part of the large multiprotein complex, which is required for ubiquitin-mediated degradation of cell cycle G1 regulators, and for the initiation of DNA replication. [provided by RefSeq, Jul 2008].
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Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
---|---|---|---|---|---|
OMIM IDMIM:116948 Ensembl IDEnsembl:ENSG00000099804 HGNC IDHGNC:HGNC:1734 PHARMGKB IDPA26265 Map Location19p13.3 |
GO terms in CDC34
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Term Type | Evidence Type | GO Term ID | GO Des. |
---|---|---|---|
CC | NAS | GO:0005634 | nucleus |
CC | TAS | GO:0005654 | nucleoplasm |
CC | IDA | GO:0005829 | cytosol |
CC | TAS | GO:0005829 | cytosol |
CC | IDA | GO:0016607 | nuclear speck |
BP | NAS | GO:0000082 | G1/S transition of mitotic cell cycle |
Gene expression in normal tissue: CDC34
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in CDC34
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Database | Pathway ID | Pathway Des. |
---|---|---|
biocarta | fbw7pathway | cyclin e destruction pathway |
biocarta | skp2e2fpathway | e2f1 destruction pathway |
reactome | R-HSA-1280218 | Adaptive Immune System |
reactome | R-HSA-168249 | Innate Immune System |
reactome | R-HSA-168256 | Immune System |
reactome | R-HSA-202403 | TCR signaling |
Gene-Drug: Aster Plot
Gene in drug-gene network: Network Plot

Gene-drug targets distribution
Gene Structure: PDB
Models in CDC34
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Model | Level | Reference ID | Tissue | Cancer | Drug | Clinical Response | Source | |
---|---|---|---|---|---|---|---|---|
No matching records found |