MSMB


Summary: The protein encoded by this gene is a member of the immunoglobulin binding factor family. It is synthesized by the epithelial cells of the prostate gland and secreted into the seminal plasma. This protein has inhibin-like activity. It may have a role as an autocrine paracrine factor in uterine, breast and other female reproductive tissues. The expression of the encoded protein is found to be decreased in prostate cancer. Two alternatively spliced transcript variants encoding different isoforms are described for this gene. The use of alternate polyadenylation sites has been found for this gene. [provided by RefSeq, Jul 2008].

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Name
OMIM ID
Ensembl ID
HGNC ID
PHARMGKB ID
Map Location
OMIM IDMIM:157145
PHARMGKB IDPA31177
Map Location10q11.22

Gene Categories:

DRUGGABLE GENOME

GO terms in MSMB


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Term Type
Evidence Type
GO Term ID
GO Des.
CC TAS GO:0005615 extracellular space
CC TAS GO:0005634 nucleus
BP ND GO:0008150 biological_process
MF ND GO:0003674 molecular_function
MF IPI GO:0005515 protein binding
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Gene expression in normal tissue: MSMB

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

undefined5Biosynthesis of secondary metabolites2Cell cycle1Mitosis1

Pathways in MSMB


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Database
Pathway ID
Pathway Des.
No matching records found

Gene-Drug: Aster Plot


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Drug ID
Drug Name
Model Num.
iGMDRD52 Rotenone 3
iGMDRD248 BRD4354 4
iGMDRD330 BRD4132 3
iGMDRD23 Gossypol 2
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Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in MSMB

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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