ZMYND10


Summary: This gene encodes a protein containing a MYND-type zinc finger domain that likely functions in assembly of the dynein motor. Mutations in this gene can cause primary ciliary dyskinesia. This gene is also considered a tumor suppressor gene and is often mutated, deleted, or hypermethylated and silenced in cancer cells. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2015].

NameOMIM IDEnsembl IDHGNC IDPHARMGKB IDMap Location
zinc finger MYND-type containing 10MIM:607070Ensembl:ENSG00000004838HGNC:HGNC:19412PA1349816493p21.31

GO terms in ZMYND10


Term TypeEvidence TypeGO Term IDGO Des.
BPIBAGO:0036158outer dynein arm assembly
BPIMPGO:0036158outer dynein arm assembly
BPISSGO:0036158outer dynein arm assembly
BPIBAGO:0036159inner dynein arm assembly
BPIMPGO:0036159inner dynein arm assembly
BPISSGO:0036159inner dynein arm assembly
BPIBAGO:0044458motile cilium assembly
BPIMPGO:0044458motile cilium assembly
BPISSGO:1905505positive regulation of motile cilium assembly
CCIBAGO:0005737cytoplasm
CCIDAGO:0005737cytoplasm
CCISSGO:0016324apical plasma membrane
CCIBAGO:0034451centriolar satellite
CCISSGO:0034451centriolar satellite
MFIPIGO:0005515protein binding
MFIEAGO:0046872metal ion binding

Gene expression in normal tissue: ZMYND10

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in ZMYND10


DatabasePathway IDPathway Des.

Gene-Drug: Aster Plot


Drug IDDrug NameModel Num.
iGMDRD901ELCPK3
iGMDRD61Kinetin riboside3
iGMDRD639YK 4-2793
iGMDRD424Tamatinib3
iGMDRD144NSC953973
iGMDRD532Olaparib3
iGMDRD126Tipifarnib3
iGMDRD512nutlin 33
iGMDRD23Gossypol3
iGMDRD353PD03259011
iGMDRD74Idarubicin3
iGMDRD730Kahalalide F3
iGMDRD872BRD71373
iGMDRD286Nsc 6328396
iGMDRD871BRD63683
iGMDRD158NSC1415403

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in ZMYND10

​​​​