ZMYND10

Summary: This gene encodes a protein containing a MYND-type zinc finger domain that likely functions in assembly of the dynein motor. Mutations in this gene can cause primary ciliary dyskinesia. This gene is also considered a tumor suppressor gene and is often mutated, deleted, or hypermethylated and silenced in cancer cells. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2015].

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Name
OMIM ID
Ensembl ID
HGNC ID
PHARMGKB ID
Map Location
Namezinc finger MYND-type containing 10
OMIM IDMIM:607070
Ensembl IDEnsembl:ENSG00000004838
HGNC IDHGNC:HGNC:19412
PHARMGKB IDPA134981649
Map Location3p21.31

GO terms in ZMYND10


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Term Type
Evidence Type
GO Term ID
GO Des.
BP IBA GO:0036158 outer dynein arm assembly
BP IMP GO:0036158 outer dynein arm assembly
BP ISS GO:0036158 outer dynein arm assembly
BP IBA GO:0036159 inner dynein arm assembly
BP IMP GO:0036159 inner dynein arm assembly
BP ISS GO:0036159 inner dynein arm assembly
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Gene expression in normal tissue: ZMYND10

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in ZMYND10


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Database
Pathway ID
Pathway Des.
No matching records found

Gene-Drug: Aster Plot


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Drug ID
Drug Name
Model Num.
iGMDRD901 ELCPK 3
iGMDRD61 Kinetin riboside 3
iGMDRD639 YK 4-279 3
iGMDRD424 Tamatinib 3
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Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in ZMYND10

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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