PMAIP1

Summary:

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Name
OMIM ID
Ensembl ID
HGNC ID
PHARMGKB ID
Map Location
Namephorbol-12-myristate-13-acetate-induced protein 1
OMIM IDMIM:604959
Ensembl IDEnsembl:ENSG00000141682
HGNC IDHGNC:HGNC:9108
PHARMGKB IDPA33434
Map Location18q21.32

GO terms in PMAIP1


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Term Type
Evidence Type
GO Term ID
GO Des.
CC IDA GO:0005634 nucleus
CC IBA GO:0005739 mitochondrion
CC IDA GO:0005739 mitochondrion
CC TAS GO:0005741 mitochondrial outer membrane
CC IDA GO:0005829 cytosol
CC TAS GO:0005829 cytosol
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Gene expression in normal tissue: PMAIP1

16 tissues mixtureadiposeadrenalbrainbreastcolonheartkidneyliverlunglymph nodeovaryprostateskeletal muscletestesthyroidwhite blood cells

Gene-model tissue-cancer distribution: Bubble Plot

undefinetissue: undefine cancer: undefined model num: 0undefinedtissue: undefined cancer: PANCAN model num: 74

Gene-drug pathway distribution

undefined21Neuroactive ligand-receptor interaction1Ferroptosis1Longevity regulating pathway1p53 pathway1One carbon pool by folate1Leukocyte transendothelial migration1Genome integrity1

Pathways in PMAIP1


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Database
Pathway ID
Pathway Des.
pid myc_activpathway Validated targets of C-MYC transcriptional activation
pid p53downstreampathway Direct p53 effectors
pid tap63pathway Validated transcriptional targets of TAp63 isoforms
kegg hsa04115 p53 signaling pathway - Homo sapiens (human)
kegg hsa04210 Apoptosis - Homo sapiens (human)
kegg hsa04215 Apoptosis - multiple species - Homo sapiens (human)
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Gene-Drug: Aster Plot


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Drug ID
Drug Name
Model Num.
iGMDRD6 AM-580 3
iGMDRD171 Pemetrexed 3
iGMDRD801 2,4-dideoxy-DC-45-A2 3
iGMDRD213 SMR000068650 3
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Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in PMAIP1

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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