HASPIN
Summary:
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| histone H3 associated protein kinase | MIM:609240 | Ensembl:ENSG00000177602 | HGNC:HGNC:19682 | PA134909705 | 17p13.2 |
GO terms in HASPIN
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| BP | IDA | GO:0006468 | protein phosphorylation |
| BP | IMP | GO:0007064 | mitotic sister chromatid cohesion |
| BP | IBA | GO:0035556 | intracellular signal transduction |
| BP | IDA | GO:0035556 | intracellular signal transduction |
| BP | IMP | GO:0071459 | protein localization to chromosome, centromeric region |
| BP | IMP | GO:2000751 | histone H3-T3 phosphorylation involved in chromosome passenger complex localization to kinetochore |
| CC | IBA | GO:0005634 | nucleus |
| CC | IDA | GO:0005634 | nucleus |
| CC | IEA | GO:0005694 | chromosome |
| CC | IBA | GO:0005737 | cytoplasm |
| CC | IDA | GO:0005813 | centrosome |
| CC | IDA | GO:0005819 | spindle |
| MF | IDA | GO:0004672 | protein kinase activity |
| MF | IBA | GO:0004674 | protein serine/threonine kinase activity |
| MF | IPI | GO:0005515 | protein binding |
| MF | IDA | GO:0005524 | ATP binding |
| MF | IMP | GO:0072354 | histone kinase activity (H3-T3 specific) |
Gene expression in normal tissue: HASPIN
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in HASPIN
| Database | Pathway ID | Pathway Des. |
|---|
Gene-Drug: Aster Plot
| Drug ID | Drug Name | Model Num. |
|---|---|---|
| iGMDRD329 | Merck60 | 1 |
| iGMDRD662 | JQ-1 | 2 |
| iGMDRD100 | Zebularine | 3 |
| iGMDRD188 | Piperlongumine | 3 |
| iGMDRD871 | BRD6368 | 2 |
| iGMDRD399 | Selumetinib | 2 |
| iGMDRD74 | Idarubicin | 1 |
| iGMDRD356 | PNU-74654 | 2 |
| iGMDRD505 | Pevonedistat | 6 |
| iGMDRD64 | Parbendazole | 2 |
| iGMDRD802 | 4-methylfasudil | 1 |
| iGMDRD158 | NSC141540 | 2 |
| iGMDRD121 | GMX1778 | 5 |
| iGMDRD294 | Batimastat | 1 |
| iGMDRD187 | BRD9876 | 2 |
| iGMDRD77 | Itraconazole | 2 |
| iGMDRD870 | BRD63610 | 2 |
| iGMDRD105 | Triptolide | 4 |
| iGMDRD171 | Pemetrexed | 4 |
| iGMDRD57 | Chloropentafluorobenzene | 1 |
| iGMDRD61 | Kinetin riboside | 2 |
| iGMDRD85 | Ursolic acid | 1 |
| iGMDRD901 | ELCPK | 2 |
| iGMDRD280 | CYTOCHALASIN B | 4 |
| iGMDRD387 | CHIR-99021 | 2 |
| iGMDRD420 | Leucascandrolide A | 2 |
| iGMDRD126 | Tipifarnib | 2 |
| iGMDRD150 | RITA | 3 |
| iGMDRD424 | Tamatinib | 4 |
| iGMDRD546 | BMS-754807 | 3 |
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in HASPIN
CLASSFICATION
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