GO terms in EIF3H


Term TypeEvidence TypeGO Term IDGO Des.
BPICGO:0006413translational initiation
BPIDAGO:0006413translational initiation
BPTASGO:0006413translational initiation
BPTASGO:0006446regulation of translational initiation
CCIBAGO:0005829cytosol
CCTASGO:0005829cytosol
CCIBAGO:0005852eukaryotic translation initiation factor 3 complex
CCIDAGO:0005852eukaryotic translation initiation factor 3 complex
CCHDAGO:0016020membrane
CCIBAGO:0016282eukaryotic 43S preinitiation complex
CCIBAGO:0042788polysomal ribosome
CCHDAGO:0070062extracellular exosome
CCIEAGO:0071541eukaryotic translation initiation factor 3 complex, eIF3m
MFHDAGO:0003723RNA binding
MFIBAGO:0003743translation initiation factor activity
MFICGO:0003743translation initiation factor activity
MFIDAGO:0003743translation initiation factor activity
MFIPIGO:0005515protein binding
MFIBAGO:0008237metallopeptidase activity

Gene expression in normal tissue: EIF3H

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in EIF3H


DatabasePathway IDPathway Des.
reactomeR-HSA-156827L13a-mediated translational silencing of Ceruloplasmin expression
reactomeR-HSA-392499Metabolism of proteins
reactomeR-HSA-72613Eukaryotic Translation Initiation
reactomeR-HSA-72649Translation initiation complex formation
reactomeR-HSA-72662Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S
reactomeR-HSA-72689Formation of a pool of free 40S subunits
reactomeR-HSA-72695Formation of the ternary complex, and subsequently, the 43S complex
reactomeR-HSA-72702Ribosomal scanning and start codon recognition
reactomeR-HSA-72706GTP hydrolysis and joining of the 60S ribosomal subunit
reactomeR-HSA-72737Cap-dependent Translation Initiation
reactomeR-HSA-72766Translation
wikipathwaysWP107Translation Factors
kegghsa03013RNA transport - Homo sapiens (human)
kegghsa05162Measles - Homo sapiens (human)

Gene-Drug: Aster Plot


Drug IDDrug NameModel Num.
iGMDRD286Nsc 6328396
iGMDRD414MST-3126
iGMDRD871BRD63686
iGMDRD188Piperlongumine6
iGMDRD263AACOCF33
iGMDRD103SN-386
iGMDRD270Ciclosporin2
iGMDRD138PX 123
iGMDRD251ML1623
iGMDRD137Indisulam3
iGMDRD255SB2250023
iGMDRD318PAC-12
iGMDRD446LY 21832403
iGMDRD152179324-69-72
iGMDRD61Kinetin riboside1
iGMDRD297Austocystin D3
iGMDRD116CD4374
iGMDRD144NSC953976

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in EIF3H

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