MSI2


Summary: This gene encodes an RNA-binding protein that is a member of the Musashi protein family. The encoded protein is transcriptional regulator that targets genes involved in development and cell cycle regulation. Mutations in this gene are associated with poor prognosis in certain types of cancers. This gene has also been shown to be rearranged in certain cancer cells. [provided by RefSeq, Apr 2016].

NameOMIM IDEnsembl IDHGNC IDPHARMGKB IDMap Location
musashi RNA binding protein 2MIM:607897Ensembl:ENSG00000153944HGNC:HGNC:18585PA3859017q22

GO terms in MSI2


Term TypeEvidence TypeGO Term IDGO Des.
MFHDAGO:0003723RNA binding
MFIBAGO:0003723RNA binding
MFIPIGO:0005515protein binding
MFIEAGO:0008266poly(U) RNA binding
BPIEAGO:0048864stem cell development
BPIBAGO:0051252regulation of RNA metabolic process
CCIBAGO:0005634nucleus
CCIBAGO:0005654nucleoplasm
CCIBAGO:0005737cytoplasm
CCIEAGO:0005737cytoplasm
CCIBAGO:0005844polysome
CCIEAGO:0005844polysome

Gene expression in normal tissue: MSI2

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in MSI2


DatabasePathway IDPathway Des.
wikipathwaysWP2004miR-targeted genes in lymphocytes - TarBase
kegghsa03015mRNA surveillance pathway - Homo sapiens (human)

Gene-Drug: Aster Plot


Drug IDDrug NameModel Num.
iGMDRD280CYTOCHALASIN B3
iGMDRD318PAC-13
iGMDRD871BRD63683
iGMDRD126Tipifarnib6

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in MSI2

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