GO terms in TAL1


Term TypeEvidence TypeGO Term IDGO Des.
CCIDAGO:0000118histone deacetylase complex
CCIDAGO:0000790nuclear chromatin
CCIBAGO:0005634nucleus
CCIDAGO:0005634nucleus
CCIDAGO:0005654nucleoplasm
CCTASGO:0005654nucleoplasm
CCIDAGO:0005667transcription factor complex
CCIDAGO:0033193Lsd1/2 complex
BPIEAGO:0000122negative regulation of transcription by RNA polymerase II
BPIEAGO:0001525angiogenesis
BPIEAGO:0006351transcription, DNA-templated
BPIBAGO:0006357regulation of transcription by RNA polymerase II
BPISSGO:0006357regulation of transcription by RNA polymerase II
BPIEAGO:0007626locomotory behavior
BPIEAGO:0021527spinal cord association neuron differentiation
BPISSGO:0030097hemopoiesis
BPIEPGO:0030218erythrocyte differentiation
BPIMPGO:0030218erythrocyte differentiation
BPIEPGO:0030219megakaryocyte differentiation
BPIEAGO:0030220platelet formation
BPIEPGO:0030221basophil differentiation
BPIDAGO:0031334positive regulation of protein complex assembly
BPISSGO:0035162embryonic hemopoiesis
BPIEAGO:0035855megakaryocyte development
BPIEAGO:0042127regulation of cell proliferation
BPIEAGO:0043249erythrocyte maturation
BPISSGO:0045165cell fate commitment
BPIDAGO:0045648positive regulation of erythrocyte differentiation
BPISSGO:0045648positive regulation of erythrocyte differentiation
BPIMPGO:0045799positive regulation of chromatin assembly or disassembly
BPIDAGO:0045893positive regulation of transcription, DNA-templated
BPIMPGO:0045931positive regulation of mitotic cell cycle
BPIDAGO:0045944positive regulation of transcription by RNA polymerase II
BPIMPGO:0051781positive regulation of cell division
BPIEAGO:0060018astrocyte fate commitment
BPIEAGO:0060216definitive hemopoiesis
BPIEAGO:0060217hemangioblast cell differentiation
BPIEAGO:0060218hematopoietic stem cell differentiation
BPIEAGO:0060375regulation of mast cell differentiation
BPTASGO:1902036regulation of hematopoietic stem cell differentiation
BPIEAGO:2000036regulation of stem cell population maintenance
MFIBAGO:0000977RNA polymerase II regulatory region sequence-specific DNA binding
MFIEAGO:0000980RNA polymerase II distal enhancer sequence-specific DNA binding
MFIBAGO:0000981RNA polymerase II transcription factor activity, sequence-specific DNA binding
MFISAGO:0000981RNA polymerase II transcription factor activity, sequence-specific DNA binding
MFISMGO:0000981RNA polymerase II transcription factor activity, sequence-specific DNA binding
MFIPIGO:0001085RNA polymerase II transcription factor binding
MFIDAGO:0003682chromatin binding
MFIDAGO:0003700DNA-binding transcription factor activity
MFIPIGO:0005515protein binding
MFIPIGO:0019899enzyme binding
MFIPIGO:0042826histone deacetylase binding
MFISSGO:0044212transcription regulatory region DNA binding
MFIEAGO:0046982protein heterodimerization activity
MFIDAGO:0070888E-box binding

Gene expression in normal tissue: TAL1

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in TAL1


DatabasePathway IDPathway Des.
reactomeR-HSA-212436Generic Transcription Pathway
reactomeR-HSA-73857RNA Polymerase II Transcription
reactomeR-HSA-74160Gene expression (Transcription)
reactomeR-HSA-8878171Transcriptional regulation by RUNX1
reactomeR-HSA-8939236RUNX1 regulates transcription of genes involved in differentiation of HSCs
wikipathwaysWP3987HDAC6 interactions

Gene-Drug: Aster Plot


Drug IDDrug NameModel Num.
iGMDRD82Quiflapon3
iGMDRD123Isoevodiamine3
iGMDRD280CYTOCHALASIN B3
iGMDRD60Quinoclamine3
iGMDRD64Parbendazole6
iGMDRD901ELCPK3
iGMDRD297Austocystin D3
iGMDRD193Fqi13
iGMDRD351GW843682X2
iGMDRD888Compound 446
iGMDRD399Selumetinib3
iGMDRD871BRD63683
iGMDRD307Manumycin A3

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in TAL1

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