SBK2
Summary:
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| SH3 domain binding kinase family member 2 | Ensembl:ENSG00000187550 | HGNC:HGNC:34416 | PA164725571 | 19q13.42 |
GO terms in SBK2
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| MF | IBA | GO:0004674 | protein serine/threonine kinase activity |
| MF | IEA | GO:0005524 | ATP binding |
| MF | IBA | GO:0048365 | Rac GTPase binding |
| BP | IBA | GO:0007266 | Rho protein signal transduction |
| BP | IBA | GO:0007346 | regulation of mitotic cell cycle |
| BP | IBA | GO:0016477 | cell migration |
| BP | IBA | GO:0023014 | signal transduction by protein phosphorylation |
| BP | IBA | GO:0030036 | actin cytoskeleton organization |
| BP | IBA | GO:0032147 | activation of protein kinase activity |
| BP | IBA | GO:0043408 | regulation of MAPK cascade |
| CC | IBA | GO:0005737 | cytoplasm |
Gene expression in normal tissue: SBK2
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in SBK2
| Database | Pathway ID | Pathway Des. |
|---|
Gene-Drug: Aster Plot
| Drug ID | Drug Name | Model Num. |
|---|---|---|
| iGMDRD268 | Cerulenin | 3 |
| iGMDRD132 | (-)-gallocatechin-3-O-gallate | 4 |
| iGMDRD154 | NSC23766 | 3 |
| iGMDRD300 | Tozasertib | 3 |
| iGMDRD60 | Quinoclamine | 3 |
| iGMDRD780 | PP-30 | 3 |
| iGMDRD68 | Paclitaxel | 1 |
| iGMDRD494 | Neopeltolide | 3 |
| iGMDRD309 | 17AAG | 1 |
| iGMDRD434 | BMS-536924 | 3 |
| iGMDRD126 | Tipifarnib | 3 |
| iGMDRD330 | BRD4132 | 3 |
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in SBK2
CLASSFICATION
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