TWF1

Summary: This gene encodes twinfilin, an actin monomer-binding protein conserved from yeast to mammals. Studies of the mouse counterpart suggest that this protein may be an actin monomer-binding protein, and its localization to cortical G-actin-rich structures may be regulated by the small GTPase RAC1. [provided by RefSeq, Jul 2008].

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Name
OMIM ID
Ensembl ID
HGNC ID
PHARMGKB ID
Map Location
Nametwinfilin actin binding protein 1
OMIM IDMIM:610932
Ensembl IDEnsembl:ENSG00000151239
HGNC IDHGNC:HGNC:9620
PHARMGKB IDPA162407406
Map Location12q12

Gene Categories:

TYROSINE KINASEKINASE

GO terms in TWF1


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Term Type
Evidence Type
GO Term ID
GO Des.
CC IBA GO:0005737 cytoplasm
CC IDA GO:0005829 cytosol
CC IBA GO:0005884 actin filament
CC ISS GO:0005911 cell-cell junction
CC HDA GO:0005925 focal adhesion
CC ISS GO:0015629 actin cytoskeleton
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Gene expression in normal tissue: TWF1

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

undefined21Biosynthesis of secondary metabolites1Apoptosis regulation1Metabolism1Cell cycle1

Pathways in TWF1


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Database
Pathway ID
Pathway Des.
No matching records found

Gene-Drug: Aster Plot


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Drug ID
Drug Name
Model Num.
iGMDRD280 CYTOCHALASIN B 2
iGMDRD466 Chaetocin 1
iGMDRD61 Kinetin riboside 9
iGMDRD237 ABT-751 1
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Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in TWF1

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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