FRS2

Summary:

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Name
OMIM ID
Ensembl ID
HGNC ID
PHARMGKB ID
Map Location
Namefibroblast growth factor receptor substrate 2
OMIM IDMIM:607743
Ensembl IDEnsembl:ENSG00000166225
HGNC IDHGNC:HGNC:16971
PHARMGKB IDPA134850063
Map Location12q15

GO terms in FRS2


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Term Type
Evidence Type
GO Term ID
GO Des.
MF TAS GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity
MF TAS GO:0005088 Ras guanyl-nucleotide exchange factor activity
MF IPI GO:0005104 fibroblast growth factor receptor binding
MF IPI GO:0005168 neurotrophin TRKA receptor binding
MF IPI GO:0005515 protein binding
MF TAS GO:0016303 1-phosphatidylinositol-3-kinase activity
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Gene expression in normal tissue: FRS2

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

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Pathways in FRS2


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Database
Pathway ID
Pathway Des.
wikipathways WP1993 Angiogenesis overview
wikipathways WP2380 Brain-Derived Neurotrophic Factor (BDNF) signaling pathway
wikipathways WP3888 VEGFA-VEGFR2 Signaling Pathway
pid fgf_pathway FGF signaling pathway
pid ret_pathway Signaling events regulated by Ret tyrosine kinase
pid shp2_pathway SHP2 signaling
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Gene-Drug: Aster Plot


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Drug ID
Drug Name
Model Num.
iGMDRD103 SN-38 5
iGMDRD330 BRD4132 1
iGMDRD116 CD437 5
iGMDRD494 Neopeltolide 1
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Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in FRS2

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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