TSSK3
Summary: This gene encodes a kinase expressed exclusively in the testis that is thought to play a role in either germ cell differentiation or mature sperm function. [provided by RefSeq, Jul 2008].
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| testis specific serine kinase 3 | MIM:607660 | Ensembl:ENSG00000162526 | HGNC:HGNC:15473 | PA37964 | 1p35.1 |
GO terms in TSSK3
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| BP | IBA | GO:0006468 | protein phosphorylation |
| BP | ISS | GO:0006468 | protein phosphorylation |
| BP | IEA | GO:0007275 | multicellular organism development |
| BP | ISS | GO:0007283 | spermatogenesis |
| BP | IEA | GO:0030154 | cell differentiation |
| BP | IBA | GO:0035556 | intracellular signal transduction |
| CC | IBA | GO:0005634 | nucleus |
| CC | IBA | GO:0005737 | cytoplasm |
| MF | ISS | GO:0000287 | magnesium ion binding |
| MF | IBA | GO:0004674 | protein serine/threonine kinase activity |
| MF | ISS | GO:0004674 | protein serine/threonine kinase activity |
| MF | IPI | GO:0005515 | protein binding |
| MF | ISS | GO:0005524 | ATP binding |
Gene expression in normal tissue: TSSK3
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in TSSK3
| Database | Pathway ID | Pathway Des. |
|---|
Gene-Drug: Aster Plot
| Drug ID | Drug Name | Model Num. |
|---|---|---|
| iGMDRD889 | Compound 7d-cis | 3 |
| iGMDRD330 | BRD4132 | 3 |
| iGMDRD137 | Indisulam | 2 |
| iGMDRD77 | Itraconazole | 6 |
| iGMDRD781 | Sirolimus | 3 |
| iGMDRD494 | Neopeltolide | 3 |
| iGMDRD872 | BRD7137 | 3 |
| iGMDRD286 | Nsc 632839 | 3 |
| iGMDRD188 | Piperlongumine | 3 |
| iGMDRD154 | NSC23766 | 3 |
| iGMDRD132 | (-)-gallocatechin-3-O-gallate | 4 |
| iGMDRD268 | Cerulenin | 3 |
| iGMDRD280 | CYTOCHALASIN B | 1 |
| iGMDRD60 | Quinoclamine | 2 |
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in TSSK3
CLASSFICATION
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