CD79A


Summary: The B lymphocyte antigen receptor is a multimeric complex that includes the antigen-specific component, surface immunoglobulin (Ig). Surface Ig non-covalently associates with two other proteins, Ig-alpha and Ig-beta, which are necessary for expression and function of the B-cell antigen receptor. This gene encodes the Ig-alpha protein of the B-cell antigen component. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008].

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Name
OMIM ID
Ensembl ID
HGNC ID
PHARMGKB ID
Map Location
OMIM IDMIM:112205
PHARMGKB IDPA26237
Map Location19q13.2

GO terms in CD79A


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Term Type
Evidence Type
GO Term ID
GO Des.
BP IEA GO:0002250 adaptive immune response
BP IBA GO:0030183 B cell differentiation
BP ISS GO:0030183 B cell differentiation
BP ISS GO:0042100 B cell proliferation
BP ISS GO:0042113 B cell activation
BP IBA GO:0050853 B cell receptor signaling pathway
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Gene expression in normal tissue: CD79A

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in CD79A


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Database
Pathway ID
Pathway Des.
reactome R-HSA-1280218 Adaptive Immune System
reactome R-HSA-1280218 Adaptive Immune System
reactome R-HSA-168256 Immune System
reactome R-HSA-168256 Immune System
reactome R-HSA-5690714 CD22 mediated BCR regulation
reactome R-HSA-983695 Antigen activates B Cell Receptor (BCR) leading to generation of second messengers
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Gene-Drug: Aster Plot


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Drug ID
Drug Name
Model Num.
iGMDRD60 Quinoclamine 3
iGMDRD154 NSC23766 3
iGMDRD132 (-)-gallocatechin-3-O-gallate 4
iGMDRD353 PD0325901 2
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Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in CD79A

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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