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PNCK

Summary: PNCK is a member of the calcium/calmodulin-dependent protein kinase family of protein serine/threonine kinases (see CAMK1; MIM 604998) (Gardner et al., 2000 [PubMed 10673339]).[supplied by OMIM, Mar 2008].

Name	OMIM ID	Ensembl ID	HGNC ID	PHARMGKB ID	Map Location
pregnancy up-regulated nonubiquitous CaM kinase	MIM:300680	Ensembl:ENSG00000130822	HGNC:HGNC:13415	PA134988711	Xq28

Gene Categories:

DRUGGABLE GENOME KINASE SERINE THREONINE KINASE

GO terms in PNCK

Term Type	Evidence Type	GO Term ID	GO Des.
MF	IBA	GO:0004674	protein serine/threonine kinase activity
MF	IBA	GO:0004683	calmodulin-dependent protein kinase activity
MF	IBA	GO:0005516	calmodulin binding
MF	IEA	GO:0005516	calmodulin binding
MF	IEA	GO:0005524	ATP binding
BP	IBA	GO:0018105	peptidyl-serine phosphorylation
BP	IBA	GO:0018107	peptidyl-threonine phosphorylation
BP	IBA	GO:0035556	intracellular signal transduction
CC	IBA	GO:0005622	intracellular
CC	IEA	GO:0005634	nucleus
CC	IEA	GO:0005737	cytoplasm

Gene expression in normal tissue: PNCK

Select Project:

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in PNCK

Database	Pathway ID	Pathway Des.

Gene-Drug: Aster Plot

Drug ID	Drug Name	Model Num.
iGMDRD524	ISX-9	3
iGMDRD451	Serdemetan	1
iGMDRD300	Tozasertib	2
iGMDRD329	Merck60	2
iGMDRD577	BIX01294	3
iGMDRD506	Fedratinib	2
iGMDRD780	PP-30	3
iGMDRD318	PAC-1	6
iGMDRD226	ML006	3
iGMDRD77	Itraconazole	2
iGMDRD294	Batimastat	2
iGMDRD782	DC-45-A2	3
iGMDRD227	Fatostatin A	7
iGMDRD474	Avrainvillamide	3
iGMDRD494	Neopeltolide	6
iGMDRD781	Sirolimus	3
iGMDRD889	Compound 7d-cis	4
iGMDRD772	BRD4770	3
iGMDRD148	Pifithrin-mu	3
iGMDRD48	Dexamethasone	5
iGMDRD126	Tipifarnib	5

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in PNCK

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DATATYPES

CLASSFICATION

Disclaimer: iGMDR is intended for research purposes only. Its information cannot be used for emergencies or medical or professional advice.