ZNF668
Summary:
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| zinc finger protein 668 | MIM:617103 | Ensembl:ENSG00000167394 | HGNC:HGNC:25821 | PA142670515 | 16p11.2 |
GO terms in ZNF668
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| MF | IEA | GO:0000978 | RNA polymerase II proximal promoter sequence-specific DNA binding |
| MF | ISA | GO:0000981 | RNA polymerase II transcription factor activity, sequence-specific DNA binding |
| MF | IEA | GO:0001078 | transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding |
| MF | IEA | GO:0046872 | metal ion binding |
| BP | IEA | GO:0000122 | negative regulation of transcription by RNA polymerase II |
| BP | IEA | GO:0006351 | transcription, DNA-templated |
| CC | IEA | GO:0005634 | nucleus |
Gene expression in normal tissue: ZNF668
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in ZNF668
| Database | Pathway ID | Pathway Des. |
|---|---|---|
| reactome | R-HSA-212436 | Generic Transcription Pathway |
| reactome | R-HSA-73857 | RNA Polymerase II Transcription |
| reactome | R-HSA-74160 | Gene expression (Transcription) |
Gene-Drug: Aster Plot
| Drug ID | Drug Name | Model Num. |
|---|---|---|
| iGMDRD781 | Sirolimus | 2 |
| iGMDRD494 | Neopeltolide | 3 |
| iGMDRD523 | Cyanoquinoline, 11 | 3 |
| iGMDRD345 | Compound 10b [PMID: 11504634] | 3 |
| iGMDRD144 | NSC95397 | 2 |
| iGMDRD772 | BRD4770 | 2 |
| iGMDRD330 | BRD4132 | 3 |
| iGMDRD132 | (-)-gallocatechin-3-O-gallate | 3 |
| iGMDRD466 | Chaetocin | 3 |
| iGMDRD123 | Isoevodiamine | 1 |
| iGMDRD61 | Kinetin riboside | 1 |
| iGMDRD351 | GW843682X | 2 |
| iGMDRD52 | Rotenone | 3 |
| iGMDRD213 | SMR000068650 | 3 |
| iGMDRD255 | SB225002 | 2 |
| iGMDRD23 | Gossypol | 2 |
| iGMDRD60 | Quinoclamine | 5 |
| iGMDRD888 | Compound 44 | 3 |
| iGMDRD506 | Fedratinib | 2 |
| iGMDRD872 | BRD7137 | 2 |
| iGMDRD74 | Idarubicin | 2 |
| iGMDRD286 | Nsc 632839 | 2 |
| iGMDRD188 | Piperlongumine | 2 |
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in ZNF668
CLASSFICATION
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