CAMK4
Summary: The product of this gene belongs to the serine/threonine protein kinase family, and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. This enzyme is a multifunctional serine/threonine protein kinase with limited tissue distribution, that has been implicated in transcriptional regulation in lymphocytes, neurons and male germ cells. [provided by RefSeq, Jul 2008].
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Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
OMIM IDMIM:114080 Ensembl IDEnsembl:ENSG00000152495 HGNC IDHGNC:HGNC:1464 PHARMGKB IDPA26050 Map Location5q22.1 | |||||
GO terms in CAMK4
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Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| MF | IBA | GO:0004683 | calmodulin-dependent protein kinase activity |
| MF | IDA | GO:0004683 | calmodulin-dependent protein kinase activity |
| MF | IBA | GO:0005516 | calmodulin binding |
| MF | IEA | GO:0005524 | ATP binding |
| MF | IBA | GO:0009931 | calcium-dependent protein serine/threonine kinase activity |
| CC | IDA | GO:0001650 | fibrillar center |
Gene expression in normal tissue: CAMK4
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in CAMK4
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Database | Pathway ID | Pathway Des. |
|---|---|---|
| biocarta | cacampathway | ca-calmodulin-dependent protein kinase activation |
| biocarta | nfatpathway | nfat and hypertrophy of the heart |
| biocarta | pgc1apathway | regulation of pgc-1a |
| biocarta | stathminpathway | stathmin and breast cancer resistance to antimicrotubule agents |
| reactome | R-HSA-111885 | Opioid Signalling |
| reactome | R-HSA-111885 | Opioid Signalling |
Gene-Drug: Aster Plot
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in CAMK4
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Model | Level | Reference ID | Tissue | Cancer | Drug | Clinical Response | Source | |
|---|---|---|---|---|---|---|---|---|
| No matching records found | ||||||||
CLASSFICATION
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