COA3
Summary: This gene encodes a member of the cytochrome c oxidase assembly factor family. Studies of a related gene in fly suggest that the encoded protein is localized to mitochondria and is essential for cytochrome c oxidase function. [provided by RefSeq, Nov 2012].
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| cytochrome c oxidase assembly factor 3 | MIM:614775 | Ensembl:ENSG00000183978 | HGNC:HGNC:24990 | PA142672172 | 17q21.2 |
GO terms in COA3
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| MF | IPI | GO:0005515 | protein binding |
| CC | IDA | GO:0005739 | mitochondrion |
| CC | IDA | GO:0031305 | integral component of mitochondrial inner membrane |
| BP | IMP | GO:0033617 | mitochondrial respiratory chain complex IV assembly |
| BP | IMP | GO:0070131 | positive regulation of mitochondrial translation |
Gene expression in normal tissue: COA3
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Gene-Drug: Aster Plot
| Drug ID | Drug Name | Model Num. |
|---|---|---|
| iGMDRD147 | Prima-1 | 1 |
| iGMDRD398 | Sepantronium | 3 |
| iGMDRD772 | BRD4770 | 3 |
| iGMDRD512 | nutlin 3 | 3 |
| iGMDRD887 | Compound 23 citrate | 2 |
| iGMDRD126 | Tipifarnib | 3 |
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in COA3
CLASSFICATION
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