COA3

Summary: This gene encodes a member of the cytochrome c oxidase assembly factor family. Studies of a related gene in fly suggest that the encoded protein is localized to mitochondria and is essential for cytochrome c oxidase function. [provided by RefSeq, Nov 2012].

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Name
OMIM ID
Ensembl ID
HGNC ID
PHARMGKB ID
Map Location
Namecytochrome c oxidase assembly factor 3
OMIM IDMIM:614775
Ensembl IDEnsembl:ENSG00000183978
HGNC IDHGNC:HGNC:24990
PHARMGKB IDPA142672172
Map Location17q21.2

GO terms in COA3


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Term Type
Evidence Type
GO Term ID
GO Des.
MF IPI GO:0005515 protein binding
CC IDA GO:0005739 mitochondrion
CC IDA GO:0031305 integral component of mitochondrial inner membrane
BP IMP GO:0033617 mitochondrial respiratory chain complex IV assembly
BP IMP GO:0070131 positive regulation of mitochondrial translation
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Gene expression in normal tissue: COA3

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

undefined5Apoptosis regulation1

Pathways in COA3


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Database
Pathway ID
Pathway Des.
kegg hsa04714 Thermogenesis - Homo sapiens (human)
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Gene-Drug: Aster Plot


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Drug ID
Drug Name
Model Num.
iGMDRD147 Prima-1 1
iGMDRD398 Sepantronium 3
iGMDRD772 BRD4770 3
iGMDRD512 nutlin 3 3
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Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in COA3

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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