PSIP1
Summary:
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| PC4 and SFRS1 interacting protein 1 | MIM:603620 | Ensembl:ENSG00000164985 | HGNC:HGNC:9527 | PA33872 | 9p22.3 |
GO terms in PSIP1
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| CC | IDA | GO:0005654 | nucleoplasm |
| CC | TAS | GO:0005654 | nucleoplasm |
| CC | TAS | GO:0005829 | cytosol |
| CC | ISS | GO:0035327 | transcriptionally active chromatin |
| BP | IDA | GO:0000395 | mRNA 5'-splice site recognition |
| BP | IEA | GO:0006351 | transcription, DNA-templated |
| BP | IEA | GO:0006355 | regulation of transcription, DNA-templated |
| BP | ISS | GO:0006979 | response to oxidative stress |
| BP | ISS | GO:0009408 | response to heat |
| BP | TAS | GO:0051169 | nuclear transport |
| BP | TAS | GO:0075713 | establishment of integrated proviral latency |
| MF | HDA | GO:0003723 | RNA binding |
| MF | IPI | GO:0005515 | protein binding |
| MF | ISS | GO:0097100 | supercoiled DNA binding |
Gene expression in normal tissue: PSIP1
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in PSIP1
| Database | Pathway ID | Pathway Des. |
|---|---|---|
| reactome | R-HSA-162587 | HIV Life Cycle |
| reactome | R-HSA-162592 | Integration of provirus |
| reactome | R-HSA-162594 | Early Phase of HIV Life Cycle |
| reactome | R-HSA-162906 | HIV Infection |
| reactome | R-HSA-162909 | Host Interactions of HIV factors |
| reactome | R-HSA-1643685 | Disease |
| reactome | R-HSA-164843 | 2-LTR circle formation |
| reactome | R-HSA-175567 | Integration of viral DNA into host genomic DNA |
| reactome | R-HSA-176033 | Interactions of Vpr with host cellular proteins |
| reactome | R-HSA-177539 | Autointegration results in viral DNA circles |
| reactome | R-HSA-180689 | APOBEC3G mediated resistance to HIV-1 infection |
| reactome | R-HSA-180910 | Vpr-mediated nuclear import of PICs |
| reactome | R-HSA-5663205 | Infectious disease |
Gene-Drug: Aster Plot
| Drug ID | Drug Name | Model Num. |
|---|---|---|
| iGMDRD193 | Fqi1 | 3 |
| iGMDRD237 | ABT-751 | 1 |
| iGMDRD639 | YK 4-279 | 3 |
| iGMDRD316 | N9-Isopropyl-olomoucine | 2 |
| iGMDRD446 | LY 2183240 | 3 |
| iGMDRD123 | Isoevodiamine | 3 |
| iGMDRD679 | Bistramide A | 3 |
| iGMDRD387 | CHIR-99021 | 2 |
| iGMDRD433 | Lexibulin | 1 |
| iGMDRD781 | Sirolimus | 7 |
| iGMDRD345 | Compound 10b [PMID: 11504634] | 2 |
| iGMDRD560 | MK-2206 | 2 |
| iGMDRD562 | Navitoclax | 5 |
| iGMDRD577 | BIX01294 | 2 |
| iGMDRD188 | Piperlongumine | 3 |
| iGMDRD60 | Quinoclamine | 8 |
| iGMDRD64 | Parbendazole | 3 |
| iGMDRD255 | SB225002 | 3 |
| iGMDRD474 | Avrainvillamide | 3 |
| iGMDRD138 | PX 12 | 2 |
| iGMDRD318 | PAC-1 | 3 |
| iGMDRD782 | DC-45-A2 | 2 |
| iGMDRD434 | BMS-536924 | 3 |
| iGMDRD6 | AM-580 | 2 |
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in PSIP1
CLASSFICATION
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