REM1


Summary: The protein encoded by this gene is a GTPase and member of the RAS-like GTP-binding protein family. The encoded protein is expressed in endothelial cells, where it promotes reorganization of the actin cytoskeleton and morphological changes in the cells. [provided by RefSeq, Jul 2008].

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Name
OMIM ID
Ensembl ID
HGNC ID
PHARMGKB ID
Map Location

Gene Categories:

TRANSPORTERION CHANNEL

GO terms in REM1


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Term Type
Evidence Type
GO Term ID
GO Des.
MF IEA GO:0003924 GTPase activity
MF IBA GO:0005246 calcium channel regulator activity
MF IEA GO:0005516 calmodulin binding
MF IBA GO:0005525 GTP binding
MF IEA GO:0005525 GTP binding
BP IEA GO:0007165 signal transduction
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Gene expression in normal tissue: REM1

Gene-model tissue-cancer distribution: Bubble Plot

LUNtissue: LUN cancer: LUNG model num: 0LUNGtissue: LUNG cancer: undefined model num: 14undefinetissue: undefine cancer: undefined model num: 0undefinedtissue: undefined cancer: ADENOCARCINOMA model num: 10undefinedtissue: undefined cancer: PANCAN model num: 24BLOOtissue: BLOO cancer: BLOOD model num: 0BLOODtissue: BLOOD cancer: undefined model num: 3UTERUtissue: UTERU cancer: UTERUS model num: 0UTERUStissue: UTERUS cancer: Endometrial Carcinoma (UCEC) model num: 4

Gene-drug pathway distribution

undefined17Mitosis1Other, kinases1p53 pathway1Apoptosis regulation1PI3K/MTOR signaling1IGFR signaling1Biosynthesis of secondary metabolites1

Pathways in REM1


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Database
Pathway ID
Pathway Des.
No matching records found

Gene-Drug: Aster Plot


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Drug ID
Drug Name
Model Num.
iGMDRD150 RITA 3
iGMDRD560 MK-2206 1
iGMDRD144 NSC95397 1
iGMDRD546 BMS-754807 1
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Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in REM1

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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