GOLPH3


Summary: The Golgi complex plays a key role in the sorting and modification of proteins exported from the endoplasmic reticulum. The protein encoded by this gene is a peripheral membrane protein of the Golgi stack and may have a regulatory role in Golgi trafficking. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of these variants has not been determined. [provided by RefSeq, Jul 2008].

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Name
OMIM ID
Ensembl ID
HGNC ID
PHARMGKB ID
Map Location
OMIM IDMIM:612207
PHARMGKB IDPA28812
Map Location5p13.3

GO terms in GOLPH3


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Term Type
Evidence Type
GO Term ID
GO Des.
MF IPI GO:0005515 protein binding
MF IPI GO:0019899 enzyme binding
MF IBA GO:0070273 phosphatidylinositol-4-phosphate binding
MF IDA GO:0070273 phosphatidylinositol-4-phosphate binding
BP IBA GO:0006890 retrograde vesicle-mediated transport, Golgi to ER
BP IBA GO:0007030 Golgi organization
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Gene expression in normal tissue: GOLPH3

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

undefined15ERK MAPK signaling1Other, kinases1WNT signaling1PI3K/MTOR signaling1DNA replication1

Pathways in GOLPH3


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Database
Pathway ID
Pathway Des.
No matching records found

Gene-Drug: Aster Plot


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Drug ID
Drug Name
Model Num.
iGMDRD560 MK-2206 1
iGMDRD424 Tamatinib 1
iGMDRD387 CHIR-99021 2
iGMDRD126 Tipifarnib 1
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Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in GOLPH3

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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