NEDD8


Summary:

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Name
OMIM ID
Ensembl ID
HGNC ID
PHARMGKB ID
Map Location

GO terms in NEDD8


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Term Type
Evidence Type
GO Term ID
GO Des.
MF IPI GO:0005515 protein binding
MF IBA GO:0031386 protein tag
MF IBA GO:0031625 ubiquitin protein ligase binding
MF IPI GO:0031625 ubiquitin protein ligase binding
MF IBA GO:0070628 proteasome binding
BP IEA GO:0006357 regulation of transcription by RNA polymerase II
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Gene expression in normal tissue: NEDD8

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

undefined4PI3K/MTOR signaling1

Pathways in NEDD8


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Database
Pathway ID
Pathway Des.
reactome R-HSA-162582 Signal Transduction
reactome R-HSA-170834 Signaling by TGF-beta Receptor Complex
reactome R-HSA-199991 Membrane Trafficking
reactome R-HSA-2173789 TGF-beta receptor signaling activates SMADs
reactome R-HSA-382551 Transport of small molecules
reactome R-HSA-392499 Metabolism of proteins
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Gene-Drug: Aster Plot


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Drug ID
Drug Name
Model Num.
iGMDRD137 Indisulam 3
iGMDRD85 Ursolic acid 3
iGMDRD512 nutlin 3 3
iGMDRD560 MK-2206 3
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Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in NEDD8

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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