CAMK2D

Summary: The product of this gene belongs to the serine/threonine protein kinase family and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. In mammalian cells, the enzyme is composed of four different chains: alpha, beta, gamma, and delta. The product of this gene is a delta chain. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Distinct isoforms of this chain have different expression patterns.[provided by RefSeq, Nov 2008].

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Name
OMIM ID
Ensembl ID
HGNC ID
PHARMGKB ID
Map Location
Namecalcium/calmodulin dependent protein kinase II delta
OMIM IDMIM:607708
Ensembl IDEnsembl:ENSG00000145349
HGNC IDHGNC:HGNC:1462
PHARMGKB IDPA92
Map Location4q26

GO terms in CAMK2D


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Term Type
Evidence Type
GO Term ID
GO Des.
CC ISS GO:0005634 nucleus
CC TAS GO:0005654 nucleoplasm
CC IBA GO:0005737 cytoplasm
CC ISS GO:0005737 cytoplasm
CC TAS GO:0005829 cytosol
CC TAS GO:0005886 plasma membrane
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Gene expression in normal tissue: CAMK2D

Gene-model tissue-cancer distribution: Bubble Plot

undefinetissue: undefine cancer: undefined model num: 0undefinedtissue: undefined cancer: PANCAN model num: 13undefinedtissue: undefined cancer: ADENOCARCINOMA model num: 2LUNtissue: LUN cancer: LUNG model num: 0LUNGtissue: LUNG cancer: undefined model num: 15

Gene-drug pathway distribution

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Pathways in CAMK2D


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Database
Pathway ID
Pathway Des.
reactome R-HSA-112314 Neurotransmitter receptors and postsynaptic signal transmission
reactome R-HSA-112315 Transmission across Chemical Synapses
reactome R-HSA-112316 Neuronal System
reactome R-HSA-1280215 Cytokine Signaling in Immune system
reactome R-HSA-162582 Signal Transduction
reactome R-HSA-168256 Immune System
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Gene-Drug: Aster Plot


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Drug ID
Drug Name
Model Num.
iGMDRD137 Indisulam 6
iGMDRD121 GMX1778 3
iGMDRD6 AM-580 3
iGMDRD100 Zebularine 3
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Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in CAMK2D

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
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